Evidence map›Paper›PMID 39334867›Full record

ReviewBiomolecules2024

Natural Compounds for the Treatment of Acute Pancreatitis: Novel Anti-Inflammatory Therapies.

Wenkai Jiang, Xiao Li, Yi Zhang, Wence Zhou

Abstract readReview
In one paragraph

Review in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wenkai JiangThe Second Clinical Medical College, Lanzhou University, Lanzhou 730030, China.ORCID 0000-0002-2143-8680
Xiao LiThe Second Clinical Medical College, Lanzhou University, Lanzhou 730030, China.
Yi ZhangThe First Clinical Medical College, Lanzhou University, Lanzhou 730030, China.
Wence ZhouThe Second Clinical Medical College, Lanzhou University, Lanzhou 730030, China.

Funding

Cuiying Scientific Training Program for Undergraduates of The Second Hospital & Clinical Medical School, Lanzhou University CYXZ2024-30
6 · The paper itself

Abstract

Acute pancreatitis remains a serious public health problem, and the burden of acute pancreatitis is increasing. With significant morbidity and serious complications, appropriate and effective therapies are critical. Great progress has been made in understanding the pathophysiology of acute pancreatitis over the past two decades. However, specific drugs targeting key molecules and pathways involved in acute pancreatitis still require further study. Natural compounds extracted from plants have a variety of biological activities and can inhibit inflammation and oxidative stress in acute pancreatitis by blocking several signaling pathways, such as the nuclear factor kappa-B and mitogen-activated protein kinase pathways. In this article, we review the therapeutic effects of various types of phytochemicals on acute pancreatitis and discuss the mechanism of action of these natural compounds in acute pancreatitis, aiming to provide clearer insights into the treatment of acute pancreatitis.

Indexed as

Anti-Inflammatory AgentsPancreatitisAcute DiseaseAnimalsBiological ProductsHumansNF-kappa BOxidative StressPhytochemicalsSignal TransductionAnti-Inflammatory AgentsBiological ProductsNF-kappa BPhytochemicalsacute pancreatitisanti-inflammationMAPKNF-κBphytochemical

Identifiers

PMID39334867
PMCPMC11430608

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.