Evidence map›Paper›PMID 39335387›Full record

ReviewBrain sciences2024

Efficacy of rTMS Combined with Cognitive and Language Training in People Living with Alzheimer's Disease: A Systematic Review.

Eleni-Nefeli Georgopoulou, Anastasia Nousia, Maria Martzoukou, Nefeli K Dimitriou, Ioannis Liampas, Lambros Messinis, Grigorios Nasios

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eleni-Nefeli GeorgopoulouDepartment of Speech and Language Therapy, School of Health Sciences, University of Ioannina, 45332 Ioannina, Greece.
Anastasia NousiaDepartment of Speech and Language Therapy, University of Peloponnese, 24100 Kalamata, Greece.
Maria MartzoukouLaboratory of Neuropsychology and Behavioral Neuroscience, School of Psychology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Nefeli K DimitriouDepartment of Speech and Language Therapy, School of Health Sciences, University of Ioannina, 45332 Ioannina, Greece.ORCID 0000-0002-5770-4303
Ioannis LiampasDepartment of Neurology, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.ORCID 0000-0002-2958-5220
Lambros MessinisLaboratory of Neuropsychology and Behavioral Neuroscience, School of Psychology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-3216-9025
Grigorios NasiosDepartment of Speech and Language Therapy, School of Health Sciences, University of Ioannina, 45332 Ioannina, Greece.ORCID 0000-0001-7495-6863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation method that has been suggested as a possible treatment method for cognitive impairment in patients with Alzheimer's Disease (pwAD), similar to multidomain cognitive training (CT). The effectiveness, however, of combining these techniques for pwAD remains controversial due to the variability in rTMS parameters, differences in CT protocol designs-many of which neglect the language domain-and the inclusion of patients at various stages of Alzheimer's Disease (AD) and with different types of dementia. The current review aims to evaluate the cognitive benefits of combining rTMS with CT, including language training, for individuals with mild to moderate AD. An extensive literature search was conducted in PubMed, Google Scholar, and the Cochrane Library with relevant terms, resulting in nine studies with a total of 290 participants [190 in the Active Group (AG) and 100 in the Control Group (CG)]. The comprehensive review of the articles revealed that the combined treatment improved global cognitive function, as well as neurocognitive, neuropsychiatric, and quality of life in the AG. Nevertheless, these results should be interpreted cautiously, given the relatively small number of existing studies on this specific combination.

Indexed as

Alzheimercognitive and language training Alzheimercognitive training and rTMSlanguage rehabilitationrTMS

Identifiers

PMID39335387
PMCPMC11430768

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.