Evidence map›Paper›PMID 39335425›Full record

ArticleBrain sciences2024

Real-Time fMRI Neurofeedback Training of Selective Attention in Older Adults.

Tian Lin, Mohit Rana, Peiwei Liu, Rebecca Polk, Amber Heemskerk, Steven M Weisberg, Dawn Bowers, Ranganatha Sitaram, Natalie C Ebner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tian LinDepartment of Psychology, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0003-2615-3577
Mohit RanaInstitute of Biological and Medical Engineering, Department of Psychiatry and Section of Neuroscience, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.
Peiwei LiuDepartment of Psychology, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0003-2660-1106
Rebecca PolkDepartment of Psychology, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-9675-2287
Amber HeemskerkDepartment of Psychology, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-0764-0559
Steven M WeisbergDepartment of Psychology, University of Florida, Gainesville, FL 32611, USA.
Dawn BowersDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0001-7329-2014
Ranganatha SitaramSt. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-8577-8035
Natalie C EbnerDepartment of Psychology, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-2705-7520

Funding

Characterizing and Modulating Neurocognitive Processes of Learning to Trust and Distrust in Aging (Diversity Supplement)R01AG072658 · NIA · UNIVERSITY OF FLORIDA · PI Natalie C Ebner, Nichole Lighthall · 2022 to 2026
$3.6M
Advanced 3T for Structural and Functional Imaging at University of FloridaS10OD021726 · OD · UNIVERSITY OF FLORIDA · PI LONG, JOANNA R · 2017 to 2017
$2.0M
Critical Life Event Support for K01 NIA AwardeeK01AG070333 · NIA · UNIVERSITY OF FLORIDA · PI WEISBERG, STEVEN M · 2021 to 2025
$694k
Determining Plasticity of Brain-Regulatory Mechanisms Related to Emotion Processing: A Neurofeedback Approach in Aging and Parkinson DiseaseR21AG057200 · NIA · UNIVERSITY OF FLORIDA · PI BOWERS, DAWN, EBNER, NATALIE C · 2017 to 2018
$419k
Florida Department of Health Ed and Ethel Moore Alzheimer's Disease Research Program 20A15Florida Department of Health Ed and Ethel Moore Alzheimer's Disease Research Program 21A09National Institute of Health/National Institute on Aging R01AG072658National Institute of Health/National Institute on Aging R21AG057200NIA NIH HHS K01 AG070333NIA NIH HHS R01 AG072658NIA NIH HHS R21 AG057200NIH HHS S10 OD021726
6 · The paper itself

Abstract

backgroundSelective attention declines with age, due to age-related functional changes in dorsal anterior cingulate cortex (dACC). Real-time functional magnetic resonance imaging (rtfMRI) neurofeedback has been used in young adults to train volitional control of brain activity, including in dACC.

methodsFor the first time, this study used rtfMRI neurofeedback to train 19 young and 27 older adults in volitional up- or down-regulation of bilateral dACC during a selective attention task.

resultsOlder participants in the up-regulation condition (experimental group) showed greater reward points and dACC BOLD signal across training sessions, reflective of neurofeedback training success; and faster reaction time and better response accuracy, suggesting behavioral benefits on selective attention. These effects were not observed for older participants in the down-regulation condition (inverse condition control group), supporting specificity of volitional dACC up-regulation training in older adults. These effects were, unexpectedly, also not observed for young participants in the up-regulation condition (age control group), perhaps due to a lack of motivation to continue the training.

conclusionsThese findings provide promising first evidence of functional plasticity in dACC in late life via rtfMRI neurofeedback up-regulation training, enhancing selective attention, and demonstrate proof of concept of rtfMRI neurofeedback training in cognitive aging.

Indexed as

dACCneurofeedback trainingold agertfMRIselective attention

Identifiers

PMID39335425
PMCPMC11430676

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.