Evidence map›Paper›PMID 39335616›Full record

ArticleBiomedicines2024

Impact of Mild COVID-19 History on Oral-Gut Microbiota and Serum Metabolomics in Adult Patients with Crohn's Disease: Potential Beneficial Effects.

Bingjie Xiang, Qi Zhang, Huibo Wu, Jue Lin, Zhaoyuan Xu, Min Zhang, Lixin Zhu, Jun Hu, Min Zhi

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Microbiome-Metabolome Crosstalk as a Driver of COVID-19 Severity.Medical sciences (Basel, Switzerland) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bingjie XiangDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.
Qi ZhangDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.
Huibo WuDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.
Jue LinDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.
Zhaoyuan XuDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.ORCID 0009-0003-7570-0132
Min ZhangDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.
Lixin ZhuGuangdong Institute of Gastroenterology, Guangzhou 510655, China.
Jun HuGuangdong Institute of Gastroenterology, Guangzhou 510655, China.
Min ZhiDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.ORCID 0000-0003-4475-4704

Funding

Guangdong Province "Pearl River Talent Plan" Innovation and Entrepreneurship Team Project 2019ZT08Y464 (LZ)"Jie Bang Gua Shuai" project of The Sixth Affiliated Hospital of Sun Yat-sen University 2022JBGS06 (MZ)the Bureau of Science and Technology of Guangzhou Municipality SL2022B03J00237 (MZ)the National Natural Science Foundation of China 82270544 (MZ)the program of Guangdong Provincial Clinical Research Center for Digestive Diseases 2020B1111170004 (MZ)the Sun Yat-sen University Clinical Research 5010 Program 2014008 (MZ)
6 · The paper itself

Abstract

The impact of coronavirus disease 2019 (COVID-19) history on Crohn's disease (CD) is unknown. This investigation aimed to examine the effect of COVID-19 history on the disease course, oral-gut microbiota, and serum metabolomics in patients with CD. In this study, oral-gut microbiota and serum metabolomic profiles in 30 patients with CD and a history of mild COVID-19 (positive group, PG), 30 patients with CD without COVID-19 history (negative group, NG), and 60 healthy controls (HC) were assessed using 16S rDNA sequencing and targeted metabolomics. During follow-up, the CD activity index showed a stronger decrease in the PG than in the NG (

Indexed as

COVID-19Crohn’s diseasegut microbiotainflammatory bowel diseasemetabolomeoral microbiota

Identifiers

PMID39335616
PMCPMC11429124

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.