Evidence mapPaperPMID 39335646Full record

ReviewBiomedicines2024

Chemerin in the Spotlight: Revealing Its Multifaceted Role in Acute Myocardial Infarction.

Andreas Mitsis, Elina Khattab, Michael Myrianthefs, Stergios Tzikas, Nikolaos P E Kadoglou, Nikolaos Fragakis, Antonios Ziakas, George Kassimis

Abstract readReview
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Chemerin/ChemerinR1 axis and inflammation-related diseases.Frontiers in molecular biosciences · 2026
    Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andreas MitsisCardiology Department, Nicosia General Hospital, State Health Services Organization, Nicosia 2029, Cyprus.ORCID 0000-0002-0286-7762
Elina KhattabCardiology Department, Nicosia General Hospital, State Health Services Organization, Nicosia 2029, Cyprus.
Michael MyrianthefsCardiology Department, Nicosia General Hospital, State Health Services Organization, Nicosia 2029, Cyprus.
Stergios TzikasThird Department of Cardiology, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0002-7811-5620
Nikolaos P E KadoglouMedical School, University of Cyprus, Nicosia 2115, Cyprus.ORCID 0000-0002-7830-3488
Nikolaos FragakisSecond Department of Cardiology, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.ORCID 0000-0002-7158-4950
Antonios ZiakasFirst Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
George KassimisSecond Department of Cardiology, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemerin, an adipokine known for its role in adipogenesis and inflammation, has emerged as a significant biomarker in cardiovascular diseases, including acute myocardial infarction (AMI). Recent studies have highlighted chemerin's involvement in the pathophysiological processes of coronary artery disease (CAD), where it modulates inflammatory responses, endothelial function, and vascular remodelling. Elevated levels of chemerin have been associated with adverse cardiovascular outcomes, including increased myocardial injury, left ventricular dysfunction, and heightened inflammatory states post-AMI. This manuscript aims to provide a comprehensive review of the current understanding of chemerin's role in AMI, detailing its molecular mechanisms, clinical implications, and potential as a biomarker for diagnosis and prognosis. Additionally, we explore the therapeutic prospects of targeting chemerin pathways to mitigate myocardial damage and improve clinical outcomes in AMI patients. By synthesizing the latest research findings, this review seeks to elucidate the multifaceted role of chemerin in AMI and its promise as a target for innovative therapeutic strategies.

Indexed as

acute myocardial infarctionadipokinesatherosclerosisbiomarkerscardiovascular diseasecardiovascular risk factorschemerincoronary artery diseaseinflammationpro-inflammatory cytokines

Identifiers

PMID39335646
PMCPMC11428948

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.