Evidence mapPaperPMID 39335873Full record

ReviewFoods (Basel, Switzerland)2024

Antioxidant Peptides and Protein Hydrolysates from Tilapia: Cellular and In Vivo Evidences for Human Health Benefits.

Wen-Jie Ng, Fai-Chu Wong, Fazilah Abd Manan, Yit-Lai Chow, Ai-Lin Ooi, Mei-Kying Ong, Xuewu Zhang, Tsun-Thai Chai

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. The effect of amylose/amylopectin ratio on the stability of starch-O/W emulsion.Journal of the science of food and agriculture · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Antioxidant Peptide-Based Nanocarriers for Delivering Wound Healing Agents.Tissue engineering and regenerative medicine · 2025
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wen-Jie NgDepartment of Allied Health Sciences, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar 31900, Malaysia.ORCID 0000-0002-5971-250X
Fai-Chu WongDepartment of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar 31900, Malaysia.ORCID 0000-0003-2259-1617
Fazilah Abd MananDepartment of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, Skudai 81310, Malaysia.
Yit-Lai ChowCenter for Agriculture and Food Research, Universiti Tunku Abdul Rahman, Kampar 31900, Malaysia.ORCID 0000-0003-3747-7366
Ai-Lin OoiCenter for Agriculture and Food Research, Universiti Tunku Abdul Rahman, Kampar 31900, Malaysia.
Mei-Kying OngCenter for Agriculture and Food Research, Universiti Tunku Abdul Rahman, Kampar 31900, Malaysia.ORCID 0000-0003-1619-6792
Xuewu ZhangCollege of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China.ORCID 0000-0001-9870-0686
Tsun-Thai ChaiDepartment of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman, Kampar 31900, Malaysia.ORCID 0000-0003-3716-1599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antioxidant peptides derived from aquatic organisms have attracted tremendous research interest due to their potential applications in human health. Tilapia is one of the most widely farmed aquaculture species globally. The current understanding of tilapia-derived antioxidant peptides is gradually expanding. This review discusses the current knowledge of peptides and protein hydrolysates derived from tilapia muscle, skin, and scales, whose antioxidant capacity has been validated in various cellular and in vivo models. To date, at least 16 peptides and several hydrolysates have been identified from tilapia that protect human and non-human cell models against oxidative injury. Tilapia hydrolysates and peptide mixtures have also shown protective effects in animal models of oxidative stress-associated diseases and exercise-induced oxidative injury and fatigue. The key mechanisms of tilapia hydrolysates and peptide mixtures involve enhancing antioxidant enzyme activities and suppressing radical production. Notably, such hydrolysates also exerted additional in vivo functions, such as anti-inflammatory, anti-diabetic, wound healing, and antiaging properties. Taken together, tilapia-derived antioxidant peptides and hydrolysates represent a valuable source of functional ingredients for applications in functional food, dietary supplements, and therapeutic applications. Continued research into their health benefits is warranted in the future.

Indexed as

antiagingantifatigueanti-inflammatoryaquaculturebioactive compoundsenzymatic hydrolysisfunctional foodoxidative stresswound healing

Identifiers

PMID39335873
PMCPMC11431209

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.