Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
17 authors.
Evandro R DiasCenter for Technological Development in Health, National Institute of Science and Technology for Innovation in Neglected Population Diseases, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.
Andressa M DuransCenter for Technological Development in Health, National Institute of Science and Technology for Innovation in Neglected Population Diseases, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.ORCID 0000-0002-0608-5813
Barbara B SuccarCenter for Technological Development in Health, National Institute of Science and Technology for Innovation in Neglected Population Diseases, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.ORCID 0000-0002-4796-5307
Luiz André L T PintoCenter for Technological Development in Health, National Institute of Science and Technology for Innovation in Neglected Population Diseases, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.ORCID 0000-0001-7539-4145
Guilherme C LechugaCenter for Technological Development in Health, National Institute of Science and Technology for Innovation in Neglected Population Diseases, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.ORCID 0000-0003-4538-3802
Mariana G MiguezLaboratório de Tecnologia Recombinante, Institute of Technology in Immunobiology, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.ORCID 0000-0002-1242-069X
Janaina Figueira-MansurLaboratório de Tecnologia Recombinante, Institute of Technology in Immunobiology, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.ORCID 0000-0001-6561-3367
Ana P C ArgondizzoLaboratório de Tecnologia Recombinante, Institute of Technology in Immunobiology, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.ORCID 0000-0001-8902-2983
Aline R BernardoLaboratório de Reativos em Diagnóstico, Institute of Technology in Immunobiology, Rio de Janeiro 21040-361, RJ, Brazil.
Rafaela L DinizLaboratório de Reativos em Diagnóstico, Institute of Technology in Immunobiology, Rio de Janeiro 21040-361, RJ, Brazil.
Gabriela S EstevesLaboratório de Tecnologia Recombinante, Institute of Technology in Immunobiology, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.
Edimilson D SilvaLaboratório de Reativos em Diagnóstico, Institute of Technology in Immunobiology, Rio de Janeiro 21040-361, RJ, Brazil.
Carlos M MorelCenter for Technological Development in Health, National Institute of Science and Technology for Innovation in Neglected Population Diseases, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.ORCID 0000-0003-2752-0009
José Borges-PereiraLaboratório de Doenças Parasitarias, Oswaldo Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.
Salvatore G De-SimoneCenter for Technological Development in Health, National Institute of Science and Technology for Innovation in Neglected Population Diseases, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.ORCID 0000-0002-2172-656X
Angela C V JunqueiraTropical Medicine Graduate Program (Stricto Sensu), Oswaldo Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.
David William ProvanceCenter for Technological Development in Health, National Institute of Science and Technology for Innovation in Neglected Population Diseases, Oswald Cruz Foundation, Rio de Janeiro 21040-361, RJ, Brazil.ORCID 0000-0002-9824-0672
Funding
Coordenação de Aperfeicoamento de Pessoal de Nível Superior #88887.493091/2020-00Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro #110.198-13; #210.470-2021; #200.960/2022Fundação Oswaldo Cruz VPPIS-004-FIO-18-52National Council for Scientific and Technological Development #465313/2014-0; 04001/2022-8; #305.157/2020-5
6 · The paper itself
Abstract
We developed a protein to rapidly and accurately diagnose Chagas disease, a life-threatening illness identified by the WHO as a critical worldwide public health risk. Limitations in present day serological tests are complicating the current health situation and contributing to most infected persons being unaware of their condition and therefore untreated. To improve diagnostic testing, we developed an immunological mimic of the etiological agent,
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.