Evidence mapPaperPMID 39337311Full record

ArticleInternational journal of molecular sciences2024

Adropin Is Expressed in Pancreatic Islet Cells and Reduces Glucagon Release in Diabetes Mellitus.

Ifrah I Ali, Crystal D'Souza, Saeed Tariq, Ernest A Adeghate

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ifrah I AliDepartment of Anatomy, College of Medicine & Health Sciences, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Crystal D'SouzaDepartment of Anatomy, College of Medicine & Health Sciences, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Saeed TariqDepartment of Anatomy, College of Medicine & Health Sciences, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.
Ernest A AdeghateDepartment of Anatomy, College of Medicine & Health Sciences, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.ORCID 0000-0002-1439-1562

Funding

United Arab Emirates University G00003388; G00002809; G00003627
6 · The paper itself

Abstract

Diabetes mellitus affects 537 million adults around the world. Adropin is expressed in different cell types. Our aim was to investigate the cellular localization in the endocrine pancreas and its effect on modulating pancreatic endocrine hormone release in streptozotocin (STZ)-induced diabetic rats. Adropin expression in the pancreas was investigated in normal and diabetic rats using immunohistochemistry and immunoelectron microscopy. Serum levels of insulin, glucagon pancreatic polypeptide (PP), and somatostatin were measured using a Luminex

Indexed as

Diabetes Mellitus, ExperimentalGlucagonInsulinIslets of LangerhansAnimalsBlood ProteinsGlucagon-Like Peptide 1Glucagon-Secreting CellsIntercellular Signaling Peptides and ProteinsIslet Amyloid PolypeptideMalePancreatic PolypeptidePeptidesRatsRats, Sprague-DawleySomatostatinBlood ProteinsENHO protein, ratGlucagonGlucagon-Like Peptide 1InsulinIntercellular Signaling Peptides and ProteinsIslet Amyloid PolypeptidePancreatic PolypeptidePeptidesSomatostatinadropindiabetes mellituselectron microscopyglucagonimmunohistochemistryinsulinpancreatic isletsratsreceptorsWestern blot

Identifiers

PMID39337311
PMCPMC11432804

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.