Evidence mapPaperPMID 39337367Full record

ReviewInternational journal of molecular sciences2024

Mass Spectrometry Advancements and Applications for Biomarker Discovery, Diagnostic Innovations, and Personalized Medicine.

Ahrum Son, Woojin Kim, Jongham Park, Yongho Park, Wonseok Lee, Sangwoon Lee, Hyunsoo Kim

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  5. Article
  6. [Advances in the application of exhaled breath analysis technology in the detection and diagnosis of liver failure].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review
  7. Review
  8. Review
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  10. Article
  11. Review
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  15. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahrum SonDepartment of Molecular Medicine, Scripps Research, San Diego, CA 92037, USA.ORCID 0000-0003-2706-1340
Woojin KimDepartment of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Republic of Korea.ORCID 0009-0001-2592-5486
Jongham ParkDepartment of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Republic of Korea.ORCID 0009-0001-5734-3800
Yongho ParkDepartment of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Republic of Korea.
Wonseok LeeDepartment of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Republic of Korea.
Sangwoon LeeDepartment of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Republic of Korea.
Hyunsoo KimDepartment of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Republic of Korea.ORCID 0000-0002-8441-3376

Funding

by Institute of Information & communications Technology Planning & Evaluation (IITP) RS-2022-00155857Korea Basic Science Institute (National research Facilities and Equipment Center) RS-2024-00402298National Research Foundation of Korea (NRF) RS-2023-00209456
6 · The paper itself

Abstract

Mass spectrometry (MS) has revolutionized clinical chemistry, offering unparalleled capabilities for biomolecule analysis. This review explores the growing significance of mass spectrometry (MS), particularly when coupled with liquid chromatography (LC), in identifying disease biomarkers and quantifying biomolecules for diagnostic and prognostic purposes. The unique advantages of MS in accurately identifying and quantifying diverse molecules have positioned it as a cornerstone in personalized-medicine advancement. MS-based technologies have transformed precision medicine, enabling a comprehensive understanding of disease mechanisms and patient-specific treatment responses. LC-MS has shown exceptional utility in analyzing complex biological matrices, while high-resolution MS has expanded analytical capabilities, allowing the detection of low-abundance molecules and the elucidation of complex biological pathways. The integration of MS with other techniques, such as ion mobility spectrometry, has opened new avenues for biomarker discovery and validation. As we progress toward precision medicine, MS-based technologies will be crucial in addressing the challenges of individualized patient care, driving innovations in disease diagnosis, prognosis, and treatment strategies.

Indexed as

BiomarkersMass SpectrometryPrecision MedicineChromatography, LiquidHumansBiomarkersbiomarker discoveryclinical chemistryliquid chromatography–mass spectrometrypersonalized medicine

Identifiers

PMID39337367
PMCPMC11432749

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.