ArticleInternational journal of molecular sciences2024
Exposure of Colon-Derived Epithelial Monolayers to Fecal Luminal Factors from Patients with Colon Cancer and Ulcerative Colitis Results in Distinct Gene Expression Patterns.
Maria K Magnusson, Anna Bas Forsberg, Alexandra Verveda, Maria Sapnara, Julie Lorent, Otto Savolainen, Yvonne Wettergren, Hans Strid, Magnus Simrén, Lena Öhman
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Maria K MagnussonDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0002-8888-4968 Anna Bas ForsbergDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden.
Alexandra VervedaDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden.
Maria SapnaraDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden.
Julie LorentNational Bioinformatics Infrastructure Stockholm (NBIS), Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, 106 91 Stockholm, Sweden.
Otto SavolainenChalmers Mass Spectrometry Infrastructure, Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Yvonne WettergrenDepartment of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden.ORCID 0000-0001-8660-7169 Hans StridDepartment of Internal Medicine, Södra Älvsborg Hospital, 501 82 Borås, Sweden.
Magnus SimrénDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden.ORCID 0000-0002-1155-1313 Lena ÖhmanDepartment of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0001-8142-2106 Funding
Adlerbertska foundation No grant numberApotekare Hedbergs foundation No grant numberFaculty of Medicine at University of Gothenburg No grant numberRegional Executive Board, Region Västra Götaland VGFOUREG-931919Regional Executive Board, Region Västra Götaland VGFOUREG-940815Sahlgrenska Academy at University of Gothenburg No grant numberSwedish Fund for Research without Animal Experiments F2021-007Swedish Fund for Research without Animal Experiments F2022-007Swedish Fund for Research without Animal Experiments S2020-033Swedish Medical Research Council 2018-02566Swedish Medical Research Council 2019-01052Swedish state under the agreement between the Swedish government and the county councils ALFGBG-722331Swedish state under the agreement between the Swedish government and the county councils ALFGBG-723921Swedish state under the agreement between the Swedish government and the county councils ALFGBG-965619Wilhelm and Martina Lundgren's foundation No grant number
6 · The paper itselfAbstract
Microbiota and luminal components may affect epithelial integrity and thus participate in the pathophysiology of colon cancer (CC) and inflammatory bowel disease (IBD). Therefore, we aimed to determine the effects of fecal luminal factors derived from patients with CC and ulcerative colitis (UC) on the colonic epithelium using a standardized colon-derived two-dimensional epithelial monolayer. The complex primary human stem cell-derived intestinal epithelium model, termed RepliGut
Indexed as
Colitis, UlcerativeColonic NeoplasmsFecesIntestinal MucosaAdultAgedCells, CulturedColonCytokinesEpithelial CellsFemaleHumansMaleMiddle AgedCytokinescolon cancerepithelial barrierepithelial monolayersinflammatory bowel diseaseintestinal microenvironment
Identifiers
PMID39337373
PMCPMC11431989
What Socratic holds
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