Evidence map›Paper›PMID 39337398›Full record

ArticleInternational journal of molecular sciences2024

Enhanced Association of Novel Cardiovascular Biomarkers Fetuin-A and Catestatin with Serological and Inflammatory Markers in Rheumatoid Arthritis Patients.

Anna Pàmies, Dídac Llop, Daiana Ibarretxe, Roser Rosales, Josefa Girona, Lluís Masana, Joan-Carles Vallvé, Silvia Paredes

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Catestatin in Cardiovascular Diseases.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna PàmiesSecció de Reumatologia, Hospital Verge de la Cinta, 43500 Tortosa, Spain.ORCID 0000-0001-5915-2656
Dídac LlopUnitat de Recerca en Lípids i Arteriosclerosi, Universitat Rovira i Virgili, 43201 Reus, Spain.
Daiana IbarretxeUnitat de Recerca en Lípids i Arteriosclerosi, Universitat Rovira i Virgili, 43201 Reus, Spain.
Roser RosalesUnitat de Recerca en Lípids i Arteriosclerosi, Universitat Rovira i Virgili, 43201 Reus, Spain.
Josefa GironaUnitat de Recerca en Lípids i Arteriosclerosi, Universitat Rovira i Virgili, 43201 Reus, Spain.ORCID 0000-0002-6267-8779
Lluís MasanaUnitat de Recerca en Lípids i Arteriosclerosi, Universitat Rovira i Virgili, 43201 Reus, Spain.ORCID 0000-0002-0789-4954
Joan-Carles VallvéUnitat de Recerca en Lípids i Arteriosclerosi, Universitat Rovira i Virgili, 43201 Reus, Spain.ORCID 0000-0001-8711-9618
Silvia ParedesUnitat de Recerca en Lípids i Arteriosclerosi, Universitat Rovira i Virgili, 43201 Reus, Spain.

Funding

Instituto de Salud Carlos III PI20/00443
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with increased cardiovascular disease (CVD) risk and mortality. This work aimed to evaluate the serum levels of the novel CV biomarkers fetuin-A (fet-A), Dickkopf-1 (DKK-1), galectin-3 (Gal-3), interleukin-32 (IL-32), and catestatin (CST) in RA patients and their associations with RA parameters and CVD markers. A cohort of 199 RA patients was assessed for traditional CVD risk factors, RA disease activity, and biomarker levels. Carotid ultrasound was used to measure carotid intima-media thickness (cIMT) and carotid plaque presence (cPP). Multivariate analyses examined correlations between biomarkers and RA parameters, serological markers, and CVD markers. Adjusted models showed that elevated CST expression levels were associated with rheumatoid factor (RF) and anti-citrullinated protein antibody (ACPA) positivity (OR = 2.45,

Indexed as

alpha-2-HS-GlycoproteinArthritis, RheumatoidBiomarkersCardiovascular DiseasesPeptide FragmentsAdultAgedAnti-Citrullinated Protein AntibodiesBlood ProteinsCarotid Intima-Media ThicknessChromogranin AFemaleGalectinsHumansIntercellular Signaling Peptides and ProteinsMaleAHSG protein, humanalpha-2-HS-GlycoproteinAnti-Citrullinated Protein AntibodiesBiomarkersBlood ProteinsCHGA protein, humanChromogranin Achromogranin A (344-364)DKK1 protein, humanGalectinsIntercellular Signaling Peptides and ProteinsLGALS3 protein, humanPeptide FragmentsRheumatoid Factoratherosclerosisbiomarkerscardiovascular diseaserheumatoid arthritis

Identifiers

PMID39337398
PMCPMC11431854

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.