Functional Interdependence of Anoctamins May Influence Conclusions from Overexpression Studies.

Jiraporn Ousingsawat, Rainer Schreiber, Karl Kunzelmann

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

LncRNA BMNCR Regulates Proliferation, Apoptosis and Inflammatory Response in Bovine Mammary Epithelial Cells Through the miR-145/ANO6 Axis.Animals : an open access journal from MDPI · 2026
Article
Recent advances in TMEM16F: structural plasticity, functional versatility, and implications for human diseases.Cell communication and signaling : CCS · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiraporn OusingsawatPhysiological Institute, University of Regensburg, University Street 31, D-93053 Regensburg, Germany.

Rainer SchreiberPhysiological Institute, University of Regensburg, University Street 31, D-93053 Regensburg, Germany.

Karl KunzelmannPhysiological Institute, University of Regensburg, University Street 31, D-93053 Regensburg, Germany.ORCID 0000-0001-6222-4593

Funding

deutsche forschungsgemeinschaft Transregio-SFB, Project-ID 509149993, TRR 374 (Project A3).

6 · The paper itself

Abstract

Anoctamin 6 (ANO6, TMEM16F) is a phospholipid (PL) scramblase that moves PLs between both plasma membrane (PM) leaflets and operates as an ion channel. It plays a role in development and is essential for hemostasis, bone mineralization and immune defense. However, ANO6 has also been shown to regulate cellular Ca

Indexed as

AnoctaminsCalciumPhospholipid Transfer ProteinsCalcium SignalingCell MembraneHEK293 CellsHumansANO6 protein, humanAnoctaminsCalciumPhospholipid Transfer ProteinsANO6anoctamin 6Ca2+ signalingion currentsphospholipid scramblingTMEM16F

Identifiers

PMID39337485

DOI10.3390/ijms25189998

PMCPMC11432102

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.