ReviewInternational journal of molecular sciences2024
The Mechanism of Zinc Oxide in Alleviating Diarrhea in Piglets after Weaning: A Review from the Perspective of Intestinal Barrier Function.
Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Age-related remodeling of the intestinal mucus barrier in pigs: implications for post-weaning diarrhea.Veterinary and animal science · 2026Article
- Zinc oxide quantum dots as an alternative to conventional ZnO: Physicochemical characterization and its application in weaned piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Maternal bis-glycinate bound zinc supplementation alters sow performance and milk metabolomic-lipidomic profiles and mitigates piglet diarrhea.Veterinary and animal science · 2026Article
- BEST4⁺ cells: a potential hub of intestinal ion transport and diarrhea manipulation.Advanced biotechnology · 2026Review
- Fisetin alleviates zinc overload-induced intestinal injury by inhibiting ferroptosis and remodeling gut microbiota in weaned piglets.Journal of animal science and biotechnology · 2026Article
- The Effect of Zinc Gluconate Supplementation on the Intestinal Microbiota and Growth Performance of Yorkshire Pigs.Animals : an open access journal from MDPI · 2026Article
- Effects of dietary zinc fulvate supplementation on egg quality, serum biochemical indices, and intestinal health of aged laying hens.AMB Express · 2026Article
- Curcumin as a Green Antibiotic Substitute: Mechanisms and Applications in Poultry Production and Health Promotion.Animals : an open access journal from MDPI · 2026Review
- Dietary iron and metal-based growth differentially modulate growth and gut microbiome of weaned piglets.Animal microbiome · 2026Article
- Bis-glycinate bound zinc supplementation in sows modulates sows and piglets gut microbiota and reduces piglet diarrhea incidence.Scientific reports · 2026Article
- Replacement of added trace minerals (zinc, copper, iron, and manganese) by a consensus bacterial 6-phytase variant in weaned pigs fed an all-vegetable diet.Journal of animal science · 2026Article
- Effects of potentiated zinc oxide and crude protein levels in low acid-binding capacity diets on growth performance and mineral status in nursery pigs.Journal of animal science · 2026Article
- Evaluation of copper feeding strategies and sources on nursery and finishing pig performance.Translational animal science · 2026Article
- The Role of Swine Gut Microbiota and Its Metabolites in Maintaining Intestinal Barrier Integrity and Mitigating Stress via the Gut-Brain Axis.Animals : an open access journal from MDPI · 2025Review
- Organic acid-preserved grain improves growth and gut health in weanling pigs fed zinc oxide free diets.Scientific reports · 2025Article
- Functional Requirements of Niacinamide for Intestinal Health and Growth Performance of Nursery Pigs.Animals : an open access journal from MDPI · 2025Article
- Comparative effects of replacing soybean meal in feeds with processed soybean meal on intestinal health and growth of nursery pigs when fed pharmacological level of zinc.Animal bioscience · 2025Article
- Effects of zinc oxide and monoglyceride blend on intestinal immune, health and microbiota responses of weanling pigs.Veterinary research communications · 2025Article
- A comparison of feeding acetylated high-amylose maize starch and zinc oxide in weaned pigs experimentally inoculated with an enterotoxigenic strain of Escherichia coli.Journal of animal science · 2025Article
- Dietary fatty acids promote gut health in weaned piglets by regulating gut microbiota and immune function.Frontiers in microbiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Weaning is one of the most challenging phases for piglets, and it is also the time when piglets are the most susceptible to diarrhea, which may result in significant economic losses for pig production. One of the dietary strategies for reducing post-weaning diarrhea (PWD) in piglets is to provide them with a pharmacological dose of zinc oxide (ZnO). However, excessive or long-term usage of high-dose ZnO has significant impacts on pig health and the ecological environment. Therefore, caution should be exercised when considering the use of high-dose ZnO for the prevention or treatment of PWD in piglets. In this paper, the significant role of zinc in animal health, the potential mode of action of ZnO in alleviating diarrhea, and the impact of innovative, highly efficient ZnO alternatives on the regulation of piglet diarrhea were reviewed to offer insights into the application of novel ZnO in pig production.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.