Evidence map›Paper›PMID 39337664›Full record

ArticleInternational journal of molecular sciences2024

Aerobic Exercise Training Protects Against Insulin Resistance, Despite Low-Sodium Diet-Induced Increased Inflammation and Visceral Adiposity.

Vanessa Del Bianco, Guilherme da Silva Ferreira, Ana Paula Garcia Bochi, Paula Ramos Pinto, Letícia Gomes Rodrigues, Luzia Naoko Shinohara Furukawa, Maristela Mitiko Okamoto, Jaíne Alves Almeida, Lizandre Keren Ramos da Silveira, Aritania Sousa Santos and 10 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Vanessa Del BiancoLaboratorio de Lipides (LIM-10), Hospital das Clinicas (HCFMUSP) da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo 01246 000, Brazil.
Guilherme da Silva FerreiraLaboratorio de Lipides (LIM-10), Hospital das Clinicas (HCFMUSP) da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo 01246 000, Brazil.
Ana Paula Garcia BochiLaboratorio de Lipides (LIM-10), Hospital das Clinicas (HCFMUSP) da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo 01246 000, Brazil.
Paula Ramos PintoLaboratorio de Lipides (LIM-10), Hospital das Clinicas (HCFMUSP) da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo 01246 000, Brazil.ORCID 0000-0002-9507-3987
Letícia Gomes RodriguesLaboratorio de Lipides (LIM-10), Hospital das Clinicas (HCFMUSP) da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo 01246 000, Brazil.
Luzia Naoko Shinohara FurukawaLaboratory of Renal Pathophysiology, Department of Internal Medicine, School of Medicine, University of São Paulo, São Paulo 01246 000, Brazil.
Maristela Mitiko OkamotoDepartment of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508 000, Brazil.ORCID 0000-0001-7844-8268
Jaíne Alves AlmeidaRheumatology Division of the Hospital das Clinicas, University of São Paulo Medical School, São Paulo 01246 000, Brazil.
Lizandre Keren Ramos da SilveiraRheumatology Division of the Hospital das Clinicas, University of São Paulo Medical School, São Paulo 01246 000, Brazil.
Aritania Sousa SantosLaboratorio de Carboidratos e Radioimunoensaios (Laboratorio de Investigações Médicas, LIM-18), Faculdade de Medicina, Universidade de Sao Paulo (FMUSP), Sao Paulo 01246 000, Brazil.
Kely Cristina Soares BispoDepartment of Pathology of the Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, FMUSP, Sao Paulo 01246 000, Brazil.
Vera Luiza CapelozziDepartment of Pathology of the Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, FMUSP, Sao Paulo 01246 000, Brazil.ORCID 0000-0001-9732-5853
Maria Lucia Correa-GiannellaLaboratorio de Carboidratos e Radioimunoensaios (Laboratorio de Investigações Médicas, LIM-18), Faculdade de Medicina, Universidade de Sao Paulo (FMUSP), Sao Paulo 01246 000, Brazil.ORCID 0000-0003-3655-4446
Alexandre Alves da SilvaDepartment of Physiology and Biophysics, Mississippi Center for Obesity Research, Cardiorenal and Metabolic Diseases Research Center, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Ana Paula Pereira VelosaRheumatology Division of the Hospital das Clinicas, University of São Paulo Medical School, São Paulo 01246 000, Brazil.
Edna Regina NakandakareLaboratorio de Lipides (LIM-10), Hospital das Clinicas (HCFMUSP) da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo 01246 000, Brazil.ORCID 0000-0003-1292-027X
Ubiratan Fabres MachadoDepartment of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508 000, Brazil.ORCID 0000-0002-8237-2435
Walcy Paganelli Rosolia TeodoroRheumatology Division of the Hospital das Clinicas, University of São Paulo Medical School, São Paulo 01246 000, Brazil.
Marisa PassarelliLaboratorio de Lipides (LIM-10), Hospital das Clinicas (HCFMUSP) da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo 01246 000, Brazil.ORCID 0000-0002-9249-4698
Sergio CatanoziLaboratorio de Lipides (LIM-10), Hospital das Clinicas (HCFMUSP) da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo 01246 000, Brazil.

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior Code 001Fundação de Amparo à Pesquisa do Estado de São Paulo #2016/15603-0
6 · The paper itself

Abstract

Dietary sodium restriction increases plasma triglycerides (TG) and total cholesterol (TC) concentrations as well as causing insulin resistance and stimulation of the renin-angiotensin-aldosterone system (RAAS) and the sympathetic nervous system. Stimulation of the angiotensin II type-1 receptor (AT1) is associated with insulin resistance, inflammation, and the inhibition of adipogenesis. The current study investigated whether aerobic exercise training (AET) mitigates or inhibits the adverse effects of dietary sodium restriction on adiposity, inflammation, and insulin sensitivity in periepididymal adipose tissue. LDL receptor knockout mice were fed either a normal-sodium (NS; 1.27% NaCl) or a low-sodium (LS; 0.15% NaCl) diet and were either subjected to AET for 90 days or kept sedentary. Body mass, blood pressure (BP), hematocrit, plasma TC, TG, glucose and 24-hour urinary sodium (U

Indexed as

AdiposityDiet, Sodium-RestrictedInflammationInsulin ResistancePhysical Conditioning, AnimalAnimalsIntra-Abdominal FatMaleMiceMice, KnockoutReceptors, LDLReceptors, LDLadipose tissueaerobic exercise trainingdietary sodium restrictiondyslipidemiainsulin resistance

Identifiers

PMID39337664
PMCPMC11432465

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.