Evidence map›Paper›PMID 39337764›Full record

ArticleMicromachines2024

Optimizing Flexible Microelectrode Designs for Enhanced Efficacy in Electrical Stimulation Therapy.

Lihong Qi, Zeru Tao, Mujie Liu, Kai Yao, Jiajie Song, Yuxuan Shang, Dan Su, Na Liu, Yongwei Jiang, Yuheng Wang

Abstract read
In one paragraph

Article in Micromachines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lihong QiNingbo Zhenhai People's Hospital Health Management Center, Ningbo 315202, China.
Zeru TaoDepartment of Otorhinolaryngology Head and Neck Surgery, Ningbo Urology and Nephrology Hospital, Ningbo 315100, China.
Mujie LiuHealth Science Center, Faculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo 315211, China.
Kai YaoHealth Science Center, Faculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo 315211, China.ORCID 0009-0001-5256-9667
Jiajie SongFunctional and Molecular Imaging Key Lab of Shaanxi Province, Department of Radiology, Tangdu Hospital, Air Force Medical University, Xi'an 710032, China.
Yuxuan ShangFunctional and Molecular Imaging Key Lab of Shaanxi Province, Department of Radiology, Tangdu Hospital, Air Force Medical University, Xi'an 710032, China.
Dan SuFunctional and Molecular Imaging Key Lab of Shaanxi Province, Department of Radiology, Tangdu Hospital, Air Force Medical University, Xi'an 710032, China.
Na LiuFunctional and Molecular Imaging Key Lab of Shaanxi Province, Department of Radiology, Tangdu Hospital, Air Force Medical University, Xi'an 710032, China.
Yongwei JiangNingbo Zhenhai People's Hospital Health Management Center, Ningbo 315202, China.
Yuheng WangFunctional and Molecular Imaging Key Lab of Shaanxi Province, Department of Radiology, Tangdu Hospital, Air Force Medical University, Xi'an 710032, China.ORCID 0000-0001-6394-1455

Funding

Logistics Science and Technology Planning Project of PLA BJZ15J001XXXScience and Technology Planning Project of Guangzhou 20190301001Zhejiang Medical Health Science and Technology Project Grant Nos. 2023RC044
6 · The paper itself

Abstract

To investigate the impact of electrode structure on Electrical Stimulation Therapy (EST) for chronic wound healing, this study designed three variants of flexible microelectrodes (FMs) with Ag-Cu coverings (ACCs), each exhibiting distinct geometrical configurations: hexagonal, cross-shaped, and serpentine. These were integrated with PPY/PDA/PANI (3/6) (full name: polypyrrole/polydopamine/polyaniline 3/6). Hydrogel dressing comprehensive animal studies, coupled with detailed electrical and mechanical modeling and simulations, were conducted to assess their performance. Results indicated that the serpentine-shaped FM outperformed its counterparts in terms of flexibility and safety, exhibiting minimal thermal effects and a reduced risk of burns. Notably, FMs with metal coverings under 3% demonstrated promising potential for optoelectronic self-powering capabilities. Additionally, simulation data highlighted the significant influence of hydrogel non-uniformity on the distribution of electrical properties across the skin surface, providing critical insights for optimizing EST protocols when employing hydrogel dressings.

Indexed as

chronic wound healingelectrical stimulation therapyflexibleMEMSserpentine structure

Identifiers

PMID39337764
PMCPMC11434305

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.