Evidence map›Paper›PMID 39337885›Full record

ArticleLife (Basel, Switzerland)2024

Euterpe Oleracea Martius (Açaí) Extract and Resistance Exercise Modulate Cardiac Parameters of Hypertensive Rats.

Pilar Barbosa de Meireles, Denise Coutinho de Miranda, Anselmo Gomes de Moura, Willian Cruz Ribeiro, Ângela Quinelato Oliveira, Luciano Bernardes Leite, Pedro Forte, Lúcia Ribeiro, Samuel G Encarnação, Luiz Otávio Guimarães-Ervilha and 7 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Pilar Barbosa de MeirelesDepartment of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil.
Denise Coutinho de MirandaDepartment of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil.
Anselmo Gomes de MouraDepartment of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil.
Willian Cruz RibeiroDepartment of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil.
Ângela Quinelato OliveiraDepartment of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil.ORCID 0009-0004-7506-7514
Luciano Bernardes LeiteLaboratory of Exercise Biology, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil.ORCID 0000-0002-3012-1327
Pedro ForteDepartment of Sports, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.ORCID 0000-0003-0184-6780
Lúcia RibeiroCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Alameda Santa Apolónia, 5300-253 Bragança, Portugal.
Samuel G EncarnaçãoDepartment of Sports, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.
Luiz Otávio Guimarães-ErvilhaDepartament of Biological Sciences, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil.
Mariana Machado-NevesDepartament of Biological Sciences, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil.ORCID 0000-0002-7416-3529
Mariana Moura E DiasDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil.ORCID 0000-0003-0822-0721
Iasmim Xisto CamposDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil.ORCID 0000-0001-9149-1930
Emily Correna Carlo ReisDepartment of Veterinary Medicine, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil.
Maria do Carmo Gouveia PeluzioDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil.ORCID 0000-0003-4665-7043
Antônio José NataliLaboratory of Exercise Biology, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil.ORCID 0000-0002-4927-4024
Victor Neiva LavoratoDepartment of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil.ORCID 0000-0001-9914-4722

Funding

Fundação de Amparo à Pesquisa do Estado de Minas Gerais - Brazil (FAPEMIG) APQ-01485-22, and Conselho Nacional de Desenvolvimento Científico e Tecnológico - Brazil (CNPQ), grant number 306956/2021-7
6 · The paper itself

Abstract

backgroundThe study evaluated the effects of resistance exercise training and açaí supplementation on cardiac parameters in hypertensive animals.

methodsFor this study, rats from the Wistar and SHR lines (spontaneously hypertensive rats) were used. The animals were divided into 5 groups: Wistar Control (C); Control Hypertensive (H); Trained Hypertensive (HT); Hypertensive and Supplemented with Açaí (HA); and Hypertensive Trained and Supplemented with Açaí (HAT). Resistance exercise training was carried out through climbing. The supplemented groups received 3 g of açaí/kg of body mass. The animals' systolic blood pressure (SBP), body mass, and physical test were measured at the beginning and end of the intervention. At the end, an echocardiographic analysis was performed. Histological analysis and oxidative stress of the LV were performed.

resultsIt was found that hypertensive animals showed an increase in SBP, and the treatments reduced this parameter. The trained groups achieved higher values of maximum carrying load. Hypertension increased the dimension of the left ventricular free wall in diastole and reduced ejection and shortening fractions. The trained groups showed improvement in ejection and shortening fractions. The H group increased the proportion of extracellular matrix and reduced the proportion of cells, with the HAT group attenuating this change. Cell diameter was greater in group H, and all treatments reduced this parameter. Hypertension increased the concentration of malondialdehyde and decreased catalase activity in LV. The treatments managed to mitigate this damage.

conclusionsIt is concluded that the treatments managed to generate positive cardiovascular adaptations, and their combination enhanced these effects.

Indexed as

açaihearthypertensionresistance exercise

Identifiers

PMID39337885
PMCPMC11433082

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.