Evidence map›Paper›PMID 39338315›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Evaluation of [

Palesa C Koatale, Mick M Welling, Sipho Mdanda, Amanda Mdlophane, John Takyi-Williams, Chrisna Durandt, Iman van den Bout, Frederik Cleeren, Mike M Sathekge, Thomas Ebenhan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Palesa C KoataleDepartment of Nuclear Medicine, University of Pretoria, Pretoria 0001, South Africa.ORCID 0000-0002-2659-0454
Mick M WellingDepartment of Radiology, Interventional Molecular Imaging Laboratory, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-2249-5601
Sipho MdandaDepartment of Nuclear Medicine, University of Pretoria, Pretoria 0001, South Africa.ORCID 0000-0003-0146-0538
Amanda MdlophaneDepartment of Nuclear Medicine, University of Pretoria, Pretoria 0001, South Africa.
John Takyi-WilliamsTherapeutics Systems Research Laboratories (TSRL), Inc., Ann Arbor, MI 48109, USA.
Chrisna DurandtDepartment of Medical Immunology, Institute for Cellular and Molecular Medicine, University of Pretoria, Pretoria 0001, South Africa.ORCID 0000-0002-5679-4669
Iman van den BoutDepartment of Physiology, University of Pretoria, Pretoria 0001, South Africa.ORCID 0000-0001-6333-1470
Frederik CleerenDepartment of Pharmacy and Pharmacological Sciences, Radiopharmaceutical Research, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-3692-1608
Mike M SathekgeDepartment of Nuclear Medicine, University of Pretoria, Pretoria 0001, South Africa.ORCID 0000-0002-2806-0625
Thomas EbenhanDepartment of Nuclear Medicine, University of Pretoria, Pretoria 0001, South Africa.ORCID 0000-0002-2038-7324

Funding

National Research Foundation DSI-NRF Innovation Doctoral Scholarship Reference No.: MND190517436945Oppenheimer Memorial Trust Award OMT Ref. 2023-1567
6 · The paper itself

Abstract

The ability of bacteria to recycle exogenous amino acid-based peptides and amino sugars for peptidoglycan biosynthesis was extensively investigated using optical imaging. In particular, fluorescent AeK-NBD was effectively utilized to study the peptidoglycan recycling pathway in Gram-negative bacteria. Based on these promising results, we were inspired to develop the radioactive AeK conjugate [

Indexed as

bacterial infectioncell wallPET imagingPET tracerpurificationquality controlsynthesis

Identifiers

PMID39338315
PMCPMC11434960

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.