Evidence mapPaperPMID 39338362Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Gastrodin Alleviates Angiotensin II-Induced Hypertension and Myocardial Apoptosis via Inhibition of the PRDX2/p53 Pathway In Vivo and In Vitro.

Nanhui Xu, Qiurong Xie, Youqin Chen, Jiapeng Li, Xiuli Zhang, Huifang Zheng, Ying Cheng, Meizhu Wu, Aling Shen, Lihui Wei and 6 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Nanhui XuAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Qiurong XieAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Youqin ChenDepartment of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Jiapeng LiDepartment of Physical Education, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Xiuli ZhangAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Huifang ZhengAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Ying ChengAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Meizhu WuAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Aling ShenAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Lihui WeiAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Mengying YaoAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Yanyan YangAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Thomas J SferraDepartment of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Anjum JafriDepartment of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Yi FangAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Jun PengAcademy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.

Funding

Cardiovascular Disease Transformation Medical Technology and Economic Integration Service Platform of Fujian Province 2021XRH004Fujian Research and Training Grants for Young and Middle-aged Leaders in HealthcareFujian University of Traditional Chinese Medicine X2020004-talentsScience and Technology Major Project of Fujian Province 2019YZ014004Scientific Research Foundation for the Top Youth Talents of Fujian University of Traditional Chinese Medicine XQB202202the National Natural Science Foundation of China U22A20372 and 82074363the Natural Science Foundation of Fujian Province 2021J01938, 2022J01840 and 2021J01940Young Elite Scientists Sponsorship Program by China Association of Chinese Medicine 2021-QNRC2-B19
6 · The paper itself

Abstract

Gastrodin, a highly potent compound found in the traditional Chinese medicine

Indexed as

angiotensin IIcardiac protectiongastrodinhypertensionmyocardial apoptosisPRDX2/p53 pathway

Identifiers

PMID39338362
PMCPMC11434704

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.