Evidence map›Paper›PMID 39339080›Full record

ArticlePolymers2024

Rheological Characterization of Genipin-Based Crosslinking Pigment and O-Carboxymethyl Chitosan-Oxidized Hyaluronic Acid In Situ Formulable Hydrogels.

Ivo Marquis Beserra Junior, Débora de Sousa Lopes, Milena Costa da Silva Barbosa, João Emídio da Silva Neto, Henrique Nunes da Silva, Marcus Vinícius Lia Fook, Rômulo Feitosa Navarro, Suédina Maria de Lima Silva

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ivo Marquis Beserra JuniorPostgraduate Program in Materials Science and Engineering, Department of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, PB, Brazil.
Débora de Sousa LopesDepartment of Chemistry, State University of Paraíba, Campina Grande 58429-500, PB, Brazil.
Milena Costa da Silva BarbosaPostgraduate Program in Materials Science and Engineering, Department of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, PB, Brazil.
João Emídio da Silva NetoPostgraduate Program in Materials Science and Engineering, Department of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, PB, Brazil.
Henrique Nunes da SilvaPostgraduate Program in Materials Science and Engineering, Department of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, PB, Brazil.ORCID 0000-0002-1947-0075
Marcus Vinícius Lia FookPostgraduate Program in Materials Science and Engineering, Department of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, PB, Brazil.
Rômulo Feitosa NavarroDepartment of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, PB, Brazil.
Suédina Maria de Lima SilvaPostgraduate Program in Materials Science and Engineering, Department of Materials Engineering, Federal University of Campina Grande, Campina Grande 58429-900, PB, Brazil.ORCID 0000-0002-2073-0989

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to develop a material capable of rapidly absorbing bodily fluids and forming a resilient, adhesive, viscoelastic hydrogel in situ to prevent post-surgical adhesions. This material was formulated using O-carboxymethyl chitosan (O-CMCS), oxidized hyaluronic acid (OHA), and a crosslinking pigment derived from genipin and glutamic acid (G/GluP). Both crosslinked (O-CMCS/OHA-G/GluP) and non-crosslinked hydrogels (O-CMCS/OHA) were evaluated using a HAAKE™ MARS™ rheometer for their potential as post-surgical barriers. A rheological analysis, including dynamic oscillatory measurements, revealed that the crosslinked hydrogels exhibited significantly higher elastic moduli (

Indexed as

physical barrierspost-surgical adhesion preventionrapid self-healingviscoelastic polymer hydrogels

Identifiers

PMID39339080
PMCPMC11435878

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.