Evidence map›Paper›PMID 39339152›Full record

ReviewPharmaceutics2024

Transforming Medicine with Nanobiotechnology: Nanocarriers and Their Biomedical Applications.

Arun Karnwal, Vikas Sharma, Gaurav Kumar, Amar Yasser Jassim, Aradhana Dohroo, Iyyakkannu Sivanesan

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arun KarnwalDepartment of Microbiology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, India.ORCID 0000-0001-6514-5647
Vikas SharmaDepartment of Molecular Biology and Genetic Engineering, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, India.
Gaurav KumarDepartment of Microbiology, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, India.ORCID 0000-0002-9464-7811
Amar Yasser JassimDepartment of Marine Vertebrate, Marine Science Center, University of Basrah, Basrah 61004, Iraq.ORCID 0000-0002-4938-2156
Aradhana DohrooSchool of Agricultural Sciences, Baddi University of Emerging Sciences and Technologies, Baddi 173405, India.
Iyyakkannu SivanesanDepartment of Environmental Health Science, Institute of Natural Science and Agriculture, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0001-7447-6392

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanobiotechnology, at the intersection of nanotechnology and biology, represents a burgeoning field poised to revolutionize medicine through the use of advanced nanocarriers. These nanocarriers, endowed with distinctive physiobiological attributes, are instrumental in diverse therapeutic domains including drug delivery for microbial infections, cancer treatment, tissue engineering, immunotherapy, and gene therapy. Despite the transformative potential, several challenges hinder their efficacy, such as limited drug capacity, suboptimal targeting, and poor solubility. This review delves into the latest advancements in nanocarrier technologies, examining their properties, associated limitations, and the innovative solutions developed to address these issues. It highlights promising nanocarrier systems like nanocomposites, micelles, hydrogels, microneedles, and artificial cells that employ advanced conjugation techniques, sustained and stimulus-responsive release mechanisms, and enhanced solubility. By exploring these novel structures and their contributions to overcoming existing barriers, the article emphasizes the vital role of interdisciplinary research in advancing nanobiotechnology. This field offers unparalleled opportunities for precise and effective therapeutic delivery, underscoring its potential to reshape healthcare through personalized, targeted treatments and improved drug performance.

Indexed as

nanobiotechnologynanocarriersnovel nanostructuresprecise therapeuticstargeted drug deliverytherapeutic approaches

Identifiers

PMID39339152
PMCPMC11435024

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.