Evidence map›Paper›PMID 39339238›Full record

ReviewPharmaceutics2024

Recent Advancements in Gallic Acid-Based Drug Delivery: Applications, Clinical Trials, and Future Directions.

Ranjit K Harwansh, Rohitas Deshmukh, Vijay Pratap Shukla, Dignesh Khunt, Bhupendra Gopalbhai Prajapati, Summya Rashid, Nemat Ali, Gehan M Elossaily, Vijendra Kumar Suryawanshi, Arun Kumar

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Recent Advances in Oral Drug Delivery Systems for BCS III Drugs.Current issues in molecular biology · 2026
    Review
  9. FeACS omega · 2025
    Article
  10. Nano-Based Technology in Glioblastoma.Molecules (Basel, Switzerland) · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ranjit K HarwanshInstitute of Pharmaceutical Research, GLA University, Mathura 281406, India.ORCID 0000-0002-9192-5265
Rohitas DeshmukhInstitute of Pharmaceutical Research, GLA University, Mathura 281406, India.ORCID 0000-0002-8962-6821
Vijay Pratap ShuklaInstitute of Pharmaceutical Research, GLA University, Mathura 281406, India.
Dignesh KhuntSchool of Pharmacy, Gujarat Technological University, Gandhinagar 382027, India.ORCID 0000-0002-8850-7468
Bhupendra Gopalbhai PrajapatiShree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Mehsana 384012, India.ORCID 0000-0001-8242-4541
Summya RashidDepartment of Pharmacology & Toxicology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O. Box 173, Al-Kharj 11942, Saudi Arabia.
Nemat AliDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-6525-4202
Gehan M ElossailyDepartment of Basic Medical Sciences, College of Medicine, AlMaarefa University, P.O. Box 71666, Riyadh 11597, Saudi Arabia.
Vijendra Kumar SuryawanshiFaculty of Pharmacy, Bharti Vishwavidyalaya, Durg 491001, India.ORCID 0000-0001-8427-337X
Arun KumarSchool of Pharmacy, Sharda University, Greater Noida 201310, India.ORCID 0009-0006-4289-0795

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gallic acid (GA) is a well-known herbal bioactive compound found in many herbs and foods like tea, wine, cashew nuts, hazelnuts, walnuts, plums, grapes, mangoes, blackberries, blueberries, and strawberries. GA has been reported for several pharmacological activities, such as antioxidant, inflammatory, antineoplastic, antimicrobial, etc. Apart from its incredible therapeutic benefits, it has been associated with low permeability and bioavailability issues, limiting their efficacy. GA belongs to BCS (Biopharmaceutics classification system) class III (high solubility and low probability). In this context, novel drug delivery approaches played a vital role in resolving these GA issues. Nanocarrier systems help improve drug moiety's physical and chemical stability by encapsulating them into a lipidic or polymeric matrix or core system. In this regard, researchers have developed a wide range of nanocarrier systems for GA, including liposomes, transfersomes, niosomes, dendrimers, phytosomes, micelles, nanoemulsions, metallic nanoparticles, solid lipid nanoparticles (SLNs), nanoparticles, nanostructured lipid carriers, polymer conjugates, etc. In the present review, different search engines like Scopus, PubMed, ScienceDirect, and Google Scholar have been referred to for acquiring recent information on the theme of the work. Therefore, this review paper aims to emphasize several novel drug delivery systems, patents, and clinical updates of GA.

Indexed as

bioavailabilitygallic acidnanocarrier systemnanotechnologypermeability

Identifiers

PMID39339238
PMCPMC11435332

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.