Evidence mapPaperPMID 39339362Full record

ArticleMolecules (Basel, Switzerland)2024

Marzia Vasarri, Maria Camilla Bergonzi, Emilija Ivanova Stojcheva, Anna Rita Bilia, Donatella Degl'Innocenti

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Foods (Basel, Switzerland) · 2026
    Article
  3. Nutrients · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marzia VasarriDepartment of Chemistry, University of Florence, Via Ugo Schiff 6, 50139 Sesto Fiorentino, Italy.ORCID 0000-0002-4241-3992
Maria Camilla BergonziDepartment of Chemistry, University of Florence, Via Ugo Schiff 6, 50139 Sesto Fiorentino, Italy.ORCID 0000-0001-5144-1330
Emilija Ivanova StojchevaNatac Biotech SL, Rita Levi Montalcini 14, 28906 Getafe, Spain.
Anna Rita BiliaDepartment of Chemistry, University of Florence, Via Ugo Schiff 6, 50139 Sesto Fiorentino, Italy.ORCID 0000-0001-8772-1895
Donatella Degl'InnocentiDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.ORCID 0000-0002-3342-5537

Funding

Bio-Based Industries Joint Undertaking under the European Union's Horizon 2020 101023256
6 · The paper itself

Abstract

High concentrations of advanced glycation end products (AGEs) have been linked to diseases, including diabetic complications. The pathophysiological effects of AGEs are mainly due to oxidative stress and inflammatory processes. Among the proteins most affected by glycation are albumin, the most abundant circulating protein, and collagen, which has a long biological half-life and is abundant in the extracellular matrix. The potential cellular damage caused by AGEs underscores the importance of identifying and developing natural AGE inhibitors. Indeed, despite initial promise, many synthetic inhibitors have been withdrawn from clinical trials due to issues such as cytotoxicity and poor pharmacokinetics. In contrast, natural products have shown significant potential in inhibiting AGE formation.

Indexed as

Glycation End Products, AdvancedOleaPlant ExtractsPlant LeavesSerum Albumin, BovineAnimalsGlucoseGlycosylationIridoid GlucosidesPolyphenolsTriterpenesGlucoseGlycation End Products, AdvancedIridoid GlucosidesoleuropeinPlant ExtractsPolyphenolsSerum Albumin, BovineTriterpenesadvanced glycation end productsalbumin glycationanti-glycationgelatin glycationOlea europaea L. leaves extractsoleuropeintriterpenes

Identifiers

PMID39339362
PMCPMC11434099

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.