Evidence map›Paper›PMID 39339471›Full record

ArticleMolecules (Basel, Switzerland)2024

Unrevealing Lithium Repositioning in the Hallmarks of Cancer: Effects of Lithium Salts (LiCl and Li

Juan Carlos García-Acosta, Alejando Israel Castillo-Montoya, Gareth Omar Rostro-Alonso, Edgar Yebrán Villegas-Vázquez, Laura Itzel Quintas-Granados, Luis Sánchez-Sánchez, Hugo López-Muñóz, Lizbeth Cariño-Calvo, Israel López-Reyes, Lilia Patricia Bustamante-Montes and 6 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Juan Carlos García-AcostaLaboratorio de Farmacogenética, UMIEZ, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.
Alejando Israel Castillo-MontoyaLaboratorio de Farmacogenética, UMIEZ, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.
Gareth Omar Rostro-AlonsoLaboratorio de Farmacogenética, UMIEZ, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.
Edgar Yebrán Villegas-VázquezLaboratorio de Farmacogenética, UMIEZ, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.ORCID 0000-0002-4093-3812
Laura Itzel Quintas-GranadosColegio de Ciencias y Humanidades, Plantel Cuautepec, Universidad Autónoma de la Ciudad de México, Ciudad de México 07160, Mexico.ORCID 0000-0002-8622-2004
Luis Sánchez-SánchezLaboratorio de Biología Molecular del Cáncer, UMIEZ, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.
Hugo López-MuñózLaboratorio de Biología Molecular del Cáncer, UMIEZ, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.
Lizbeth Cariño-CalvoFacultad de Ciencias Químicas, Universidad Veracruzana, Orizaba 94340, Mexico.
Israel López-ReyesColegio de Ciencias y Humanidades, Plantel Cuautepec, Universidad Autónoma de la Ciudad de México, Ciudad de México 07160, Mexico.
Lilia Patricia Bustamante-MontesCoordinación de Investigación, Centro Universitario Siglo XXI, Edo. de México 03100, Mexico.
Gerardo Leyva-GómezDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID 0000-0002-7940-1100
Hernán CortésLaboratorio de Medicina Genómica, Departamento de Genómica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra, Ciudad de México 14389, Mexico.ORCID 0000-0002-6147-4109
Nadia Judith Jacobo-HerreraUnidad de Bioquímica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Ciudad de México 14080, Mexico.ORCID 0000-0002-1026-3774
Rosario García-AguilarLaboratorio de Citometría de Flujo y Hematología, Diagnóstico Molecular de Leucemias y Terapia Celular (DILETEC), Ciudad de México 07800, Mexico.ORCID 0000-0003-2490-5675
Octavio Daniel Reyes-HernándezLaboratorio de Farmacogenética, UMIEZ, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.ORCID 0000-0002-2767-4799
Gabriela Figueroa-GonzálezLaboratorio de Farmacogenética, UMIEZ, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Ciudad de México 09230, Mexico.ORCID 0000-0001-8169-4478

Funding

PAPIIT-UNAM IA208422, IA206724 and IN221824
6 · The paper itself

Abstract

Lithium, a natural element, has been employed as a mental stabilizer in psychiatric treatments; however, some reports indicate it has an anticancer effect, prompting the consideration of repurposing lithium for cancer treatment. The potential anticancer use of lithium may depend on its form (salt type) and the type of cancer cells targeted. Little is known about the effects of Li

Indexed as

ApoptosisCell MovementCell ProliferationLithium ChlorideUterine Cervical NeoplasmsAntineoplastic AgentsCell CycleCell Line, TumorDrug RepositioningFemaleHeLa CellsHumansLithium CarbonateAntineoplastic AgentsLithium CarbonateLithium Chlorideapoptosis inductioncell cycle arrestcervical cancer cellslithium carbonatelithium chloridemigration inhibition

Identifiers

PMID39339471
PMCPMC11434384

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.