Evidence mapPaperPMID 39339725Full record

Trial reportNutrients2024

Efficacy, Safety and Acceptability of a Very-Low-Energy Diet in Adolescents with Obesity: A Fast Track to Health Sub-Study.

Megan L Gow, Hiba Jebeile, Eve T House, Shirley Alexander, Louise A Baur, Justin Brown, Clare E Collins, Chris T Cowell, Kaitlin Day, Sarah P Garnett and 8 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. [Research Advancements in Gastric Capacity Intervention for Childhood and Adolescent Obesity].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Pooled it
  2. Review
  3. Management of Childhood Obesity.International journal of molecular sciences · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Megan L GowSydney Medical School, The University of Sydney, Westmead, NSW 2145, Australia.
Hiba JebeileSydney Medical School, The University of Sydney, Westmead, NSW 2145, Australia.ORCID 0000-0002-8623-6174
Eve T HouseSydney Medical School, The University of Sydney, Westmead, NSW 2145, Australia.
Shirley AlexanderWeight Management Services, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
Louise A BaurSydney Medical School, The University of Sydney, Westmead, NSW 2145, Australia.
Justin BrownDepartment of Paediatric Endocrinology and Diabetes, Monash Children's Hospital, Clayton, VIC 3168, Australia.
Clare E CollinsSchool of Health Sciences, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, NSW 2308, Australia.ORCID 0000-0003-3298-756X
Chris T CowellSydney Medical School, The University of Sydney, Westmead, NSW 2145, Australia.
Kaitlin DaySchool of Agriculture, Food and Ecosystem Sciences, University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0003-3846-8568
Sarah P GarnettSydney Medical School, The University of Sydney, Westmead, NSW 2145, Australia.ORCID 0000-0001-7552-0789
Alicia GrunseitNutrition and Dietetics, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
Mary-Kate InksterDepartment of Paediatric Endocrinology and Diabetes, Monash Children's Hospital, Clayton, VIC 3168, Australia.
Cathy KwokSydney Medical School, The University of Sydney, Westmead, NSW 2145, Australia.
Sarah LangDepartment of Nutrition, Dietetics & Food, Monash University, Melbourne, VIC 3004, Australia.ORCID 0000-0003-3653-1981
Susan J PaxtonSchool of Psychology and Public Health, La Trobe University, Melbourne, VIC 3086, Australia.ORCID 0000-0002-8486-1996
Helen TrubySchool of Primary and Allied Health Care, Monash University, Melbourne, VIC 3004, Australia.
Krista A VaradyDepartment of Kinesiology and Nutrition, University of Illinois, Chicago, IL 60612, USA.
Natalie B ListerSydney Medical School, The University of Sydney, Westmead, NSW 2145, Australia.ORCID 0000-0002-9148-8632

Funding

Effects of Time-restricted Eating versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers among Adults with ObesityR01CA257807 · UNIVERSITY OF ILLINOIS AT CHICAGO · 2025 to 2025
$958k
Time restricted feeding versus daily calorie restriction: Effect on body weight, metabolic risk, and the gut microbiomeR01DK128180 · UNIVERSITY OF ILLINOIS AT CHICAGO · 2025 to 2025
$500k
National Health and Medical Research Council 1128317National Health and Medical Research Council 114574National Health and Medical Research Council 1158876National Health and Medical Research Council 2009035National Health and Medical Research Council 2009340National Health and Medical Research Council 2017139NCI NIH HHS R01 CA257807NIDDK NIH HHS R01 DK119783NIDDK NIH HHS R01 DK128180NIH HHS R01DK128180; R01CA257807; R01 DK119783
6 · The paper itself

Abstract

The aim of this study was to determine the efficacy, safety and acceptability of a 4-week very-low-energy diet (VLED) program for adolescents with obesity. Adolescents (13-17 years) with obesity and ≥1 obesity-related complication were Fast Track to Health 52-week randomized controlled trial participants. Adolescents undertook a 4-week micronutrient-complete VLED (800 kcal/day), with weekly dietitian support. Anthropometric data were recorded at baseline and week-4 and side-effects at day 3-4, week-1, -2, -3 and -4. Adolescents completed an acceptability survey at week-4. A total of 134 adolescents (14.9 ± 1.2 years, 50% male) had a 5.5 ± 2.9 kg (

Indexed as

Pediatric ObesityWeight LossAdolescentCaloric RestrictionDiet, ReducingFemaleHumansMalePatient Acceptance of Health CareTreatment Outcomeacceptabilityadolescentdietary interventionobesitysafetyvery-low-energy diet

Identifiers

PMID39339725
PMCPMC11435242

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.