ReviewNutrients2024
Chronic Use of Artificial Sweeteners: Pros and Cons.
Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of Artificial Sweeteners on Inflammation Markers: A Systematic Review of Animal Studies.Nutrients · 2025Pooled it
- Article
- Low- and no-calorie sweeteners and beverages and their associated health outcomes: an umbrella review of systematic reviews and meta-analyses.Nutrition research and practice · 2026Review
- Artificial Sweeteners and Gut Microbiota: Mechanistic Insights and Implications for Metabolic Health.Current nutrition reports · 2026Review
- Long-term sucralose exposure accelerates ovarian aging via gut microbiota dysbiosis.NPJ science of food · 2026Article
- A Clinician's Guide for Trending Cardiovascular Nutritional Controversies in 2026.JACC. Advances · 2026Review
- Stevia-derived sweeteners in reduced-sugar foods: formulation strategies, sensory optimization, nutritional evidence, and safety perspectives.Frontiers in nutrition · 2026Review
- Molecular Mechanisms of Aspartame-Induced Kidney Renal Papillary Cell Carcinoma Revealed by Network Toxicology and Molecular Docking Techniques.International journal of molecular sciences · 2025Article
- Coffee Consumption and Risk of Incident Gastrointestinal Disease: A Large Prospective Cohort Study.Food science & nutrition · 2025Article
- The Relationship Between Artificial Sweetener Intake from Soft Drinks and Internet Addiction Among Students: An Analytical and Cross-Sectional Study.International journal of environmental research and public health · 2025Article
- Advancements in Microbial Applications for Sustainable Food Production.Foods (Basel, Switzerland) · 2025Review
- Artificial Sweetener Use in Hungary: A Cross-Sectional Study on Socioeconomic and Health Disparities from a Public Health Perspective.Nutrients · 2025Article
- Glycemic response to SSBs and ASBs: the role of mixed meals and individual variability.Nutrition journal · 2025Article
- Aspartame and Human Health: A Mini-Review of Carcinogenic and Systemic Effects.Journal of xenobiotics · 2025Review
- Artificial Sweeteners in Food Products: Concentration Analysis, Label Practices, and Cumulative Intake Assessment in Croatia.Nutrients · 2025Article
- Gut dysbiosis and immune dysfunction induced by chronic cola replacement of water in rats: not just a sugar problem.Frontiers in nutrition · 2025Article
- Synthetic vs. non-synthetic sweeteners: their differential effects on gut microbiome diversity and function.Frontiers in microbiology · 2025Article
- Non-sugar sweeteners and children: the current picture and controversies.Frontiers in nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past few decades, the scientific community has been highly concerned about the obesity epidemic. Artificial sweeteners are compounds that mimic the sweet taste of sugar but have no calories or carbohydrates; hence, they are very popular among patients suffering from diabetes or obesity, aiming to achieve glycemic and/or weight control. There are four different types of sweeteners: artificial, natural, rare sugars, and polyols. Artificial and natural sweeteners are characterized as non-nutritional sweeteners (NNSs) since they do not contain calories. The extended use of sweeteners has been reported to have a favorable impact on body weight and glycemic control in patients with type 2 diabetes (T2DM) and on tooth decay prevention. However, there is concern regarding their side effects. Several studies have associated artificial sweeteners' consumption with the development of insulin resistance, nonalcoholic fatty liver disease (NAFLD), gastrointestinal symptoms, and certain types of cancer. The present review focuses on the description of different types of sweeteners and the benefits and possible deleterious effects of the chronic consumption of NNSs on children's health. Additionally, possible underlying mechanisms of the unfavorable effects of NNSs on human health are described.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.