Evidence map›Paper›PMID 39340113›Full record

ArticleVaccines2024

Estimates of Potential Demand for Measles and Rubella Microarray Patches.

Lidia K Kayembe, Leah S Fischer, Bishwa B Adhikari, Jennifer K Knapp, Emily B Khan, Bradford R Greening, Mark Papania, Martin I Meltzer

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lidia K KayembeThe U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA.
Leah S FischerThe U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA.ORCID 0000-0001-9675-6133
Bishwa B AdhikariThe U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA.ORCID 0000-0003-4209-305X
Jennifer K KnappThe U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA.ORCID 0000-0003-4626-344X
Emily B KhanThe U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA.
Bradford R GreeningThe U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA.ORCID 0000-0003-2727-2287
Mark PapaniaThe U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA.
Martin I MeltzerThe U.S. Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA.ORCID 0000-0002-7250-0472

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Global measles vaccine coverage has stagnated at approximately 85% for over a decade. By simplifying vaccine logistics and administration, the measles and rubella microarray patch (MR-MAP) may improve coverage. Clinical trials have demonstrated similar safety and immunogenicity in 9-month-old infants for MR-MAPs compared with syringe-and-needle vaccination. To aid commercialization, we present estimates of MR-MAP demand. We created a spreadsheet-based tool to estimate demand for MR-MAPs using data from 180 WHO countries during 2000-2016. Five immunization scenarios were analyzed: (1a) Supplementary Immunization Activities (SIAs) in Gavi, the Vaccine Alliance (Gavi)-eligible countries and (1b) WHO countries where preventive SIAs are routinely conducted; (2) SIAs and outbreak response immunization in all WHO countries; (3) routine immunization (RI) and SIAs in six high-burden measles countries (the Democratic Republic of the Congo, Ethiopia, India, Indonesia, Nigeria, and Pakistan); (4) RI and SIAs in six high-burden countries and Gavi-eligible countries; and (5) hard-to-reach populations. MR-MAP demand varied greatly across scenarios. Forecasts for 2025-2034 estimate from 137 million doses in hard-to-reach populations (scenario 5) to 2.587 billion doses for RI and SIAs in six high-burden countries and Gavi-eligible countries (scenario 4). When policymakers and manufacturers assess MR-MAP demand, they may consider multiple scenarios to allow for a complete consideration of potential markets and public health needs.

Indexed as

health service needs and demandmeasles vaccinemicroneedlerubella vaccinetransdermal patchvaccination

Identifiers

PMID39340113
PMCPMC11436147

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.