Evidence map›Paper›PMID 39340592›Full record

ArticleCell biochemistry and biophysics2025

The Car1 Knockout Mice Exhibit Antidepressant-like Behaviors Accompanied with Gut Microbiota Disturbance.

Chong Chen, Jianjun Chen, Ke Cheng, Peng Xie

Abstract read
PubMed Publisher
In one paragraph

Article in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chong ChenNHC Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Jianjun ChenInstitute of Life Sciences, Chongqing Medical University, Chongqing, 400016, China.
Ke ChengChongqing Key Laboratory of Cerebrovascular Disease Research, Chongqing, 402100, China.
Peng XieNHC Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. xiepeng@cqmu.edu.cn.

Funding

the Chongqing Natural Science Foundation cstc2019jcyj-msxmX0025the National Key Program International Cooperation Project 81820108015the National Key R&D Program of China 2017YFA0505700the National Natural Science Foundation of China 81701361the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2019PT320002
6 · The paper itself

Abstract

Major depressive disorder (MDD) is a severe mental disorder with largely unknown mechanisms. Carbonic anhydrases convert CO

Indexed as

Behavior, AnimalCarbonic AnhydrasesDepressionGastrointestinal MicrobiomeAnimalsMajor Depressive DisorderMaleMiceMice, Inbred C57BLMice, KnockoutRNA, Ribosomal, 16SCarbonic AnhydrasesRNA, Ribosomal, 16S16S sequencingGene knockout miceMDD

Identifiers

PMID39340592

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.