Evidence map›Paper›PMID 39342143›Full record

Trial reportBMC palliative care2024

Mindfulness to enhance quality of life and support advance care planning: a pilot randomized controlled trial for adults with advanced cancer and their family caregivers.

Catherine E Mosher, Kathleen A Beck-Coon, Wei Wu, Ashley B Lewson, Patrick V Stutz, Linda F Brown, Qing Tang, Paul R Helft, Kristin Levoy, Susan E Hickman and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC palliative care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03257007 (Mindfulness to Enhance Quality of Life and Support Advance Care Planning), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03257007 nacompletednot on this map

Mindfulness to Enhance Quality of Life and Support Advance Care Planning (MEANING): A Randomized Controlled Pilot Trial for Adults With Metastatic Cancer and Their Family Caregivers

TypeinterventionalSponsorIndiana UniversityRan2017 to 2017Enrolled108ConditionsMindfulness, Meditation, Metastatic Cancer, Quality of LifeArmsMindfulness
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  8. Turning toward mortality: yoga'sFrontiers in public health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Catherine E MosherDepartment of Psychology, Indiana University Indianapolis, 402 North Blackford Street, LD 124, Indianapolis, IN, 46202, USA. cemosher@iu.edu.
Kathleen A Beck-CoonIndiana University School of Medicine, 1101 West 10th Street, Indianapolis, IN, USA.
Wei WuDepartment of Psychology, Indiana University Indianapolis, 402 North Blackford Street, LD 124, Indianapolis, IN, 46202, USA.
Ashley B LewsonDepartment of Psychology, Indiana University Indianapolis, 402 North Blackford Street, LD 124, Indianapolis, IN, 46202, USA.
Patrick V StutzIndiana University School of Medicine, 1101 West 10th Street, Indianapolis, IN, USA.
Linda F BrownIndiana University School of Medicine, 1101 West 10th Street, Indianapolis, IN, USA.
Qing TangIndiana University School of Medicine, 1101 West 10th Street, Indianapolis, IN, USA.
Paul R HelftIndiana University School of Medicine, 1101 West 10th Street, Indianapolis, IN, USA.
Kristin LevoyIndiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana Cancer Pavilion, 535 Barnhill Drive, Suite 473, Indianapolis, IN, USA.
Susan E HickmanDepartment of Community and Health Systems, Indiana University School of Nursing, 600 Barnhill Drive, Indianapolis, IN, USA.
Shelley A JohnsIndiana University School of Medicine, 1101 West 10th Street, Indianapolis, IN, USA.

Funding

Research and Training for Behavioral Oncology InterventionsK05CA175048 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI CHAMPION, VICTORIA LEE · 2014 to 2018
$484k
Indiana University Health grant number 0963NCI NIH HHS grant number K05CA175048NCI NIH HHS K05 CA175048Walther Cancer Foundation grant number 0175
6 · The paper itself

Abstract

backgroundPatients with advanced cancer and family caregivers often use avoidant coping strategies, such as delaying advance care planning discussions, which contribute to deterioration in their quality of life. Mindfulness-based interventions have shown promise in improving quality of life in this population but have rarely been applied to advance care planning. This pilot trial examined the preliminary efficacy of a group-based Mindfulness to Enhance Quality of Life and Support Advance Care Planning (MEANING) intervention for patient-caregiver dyads coping with advanced cancer. Primary outcomes were patient and caregiver quality of life or well-being, and secondary outcomes included patient advanced care planning engagement (self-efficacy and readiness) and other psychological and symptom outcomes.

methodsIn this pilot trial, dyads coping with advanced cancer were recruited from five oncology clinics in the midwestern U.S. and randomized to six weekly group sessions of a mindfulness intervention (n = 33 dyads) or usual care (n = 22 dyads). Outcomes were assessed via surveys at baseline, post-intervention, and 1 month post-intervention. All available data were included in the multilevel models assessing intervention efficacy.

resultsPatients in the MEANING condition experienced significant increases in existential well-being and self-efficacy for advance care planning across follow-ups, whereas usual care patients did not. Other group differences in outcomes were not statistically significant. These outcomes included other facets of patient well-being, caregiver quality of life, patient readiness for advance care planning, caregiver burden, and patient and caregiver depressive symptoms, anxiety, sleep disturbance, cognitive avoidance, and peaceful acceptance of cancer. However, only MEANING patients showed moderate increases in psychological well-being across follow-ups, and MEANING caregivers showed moderate increases in quality of life at 1-month follow-up. Certain psychological outcomes, such as caregiver burden at 1-month follow-up, also showed moderate improvement in the MEANING condition. Patients in both conditions reported small to moderate increases in readiness to engage in advance care planning.

conclusionsA mindfulness-based intervention showed promise in improving quality-of-life and advance care planning outcomes in patients and caregivers coping with advanced cancer and warrants further testing.

trial registrationClinicalTrials.gov NCT03257007. Registered 22 August 2017, https://clinicaltrials.gov/ct2/show/NCT03257007 .

Indexed as

Advance Care PlanningCaregiversMindfulnessNeoplasmsQuality of LifeAdaptation, PsychologicalAdultAgedFemaleHumansMaleMiddle AgedPilot ProjectsSurveys and QuestionnairesAdvance care planningClinical trialFamily caregiversMindfulnessNeoplasmsQuality of life

Identifiers

PMID39342143
PMCPMC11439323

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.