Evidence map›Paper›PMID 39342350›Full record

SynthesisJournal of orthopaedic surgery and research2024

Efficacy and safety of mind-body exercise for patients with axial spondyloarthritis: a systematic review and meta-analysis.

Jing Wang, Xinmin Li, Fangjie Yang, Pengxue Guo, Chunlin Ren, Zhengfei Duan, Yasu Zhang

Registry-linked trialAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06823726 (Efficacy and Safety of a 12-Week Taekwondo Training Program in Patients With Ankylosing Spondylitis and Axial Spondyloarthritis), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06823726 narecruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy and Safety of a 12-Week Taekwondo Training Program in Patients With Ankylosing Spondylitis and Axial Spondyloarthritis: A Randomized Controlled Trial

TypeinterventionalSponsorWonju Severance Christian HospitalRan2025 to 2025Enrolled24ConditionsAnkylosing Spondylitis, Axial SpondyloarthritisArms12-week Taekwondo training
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing WangRehabilitation Medicine College, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou, Henan, China.
Xinmin LiSchool of Traditional Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
Fangjie YangRehabilitation Medicine College, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou, Henan, China.
Pengxue GuoRehabilitation Medicine College, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou, Henan, China.
Chunlin RenRehabilitation Medicine College, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou, Henan, China.
Zhengfei DuanRehabilitation Medicine College, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou, Henan, China.
Yasu ZhangRehabilitation Medicine College, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou, Henan, China. zhangyasu16@163.com.

Funding

2023 Henan Special Research Project of TCM on "Double First-Class" Construction HSRP-DFCTCM-2023-1-21the 2023 Henan Special Research Project of TCM on "Double First-Class" Construction HSRP-DFCTCM-2023-8-23the Henan University of Chinese Medicine 2024 education and teaching reform research and practice projects 2024JX62the Science and Technology project of Henan Province 232102310466
6 · The paper itself

Abstract

objectiveTo evaluate the efficacy and safety of mind-body exercise (MBE) interventions, including Tai Chi, Yoga, Pilates, and Qigong, in patients with axial spondyloarthritis (axSpA), a systematic review and meta-analysis was conducted.

methodsEight electronic databases were searched from their inception to May 2024. RevMan 5.4 and Stata 16.0 software were used for statistical analysis. Outcome measures included Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Visual Analog Scale (VAS), Bath Ankylosing Spondylitis Metrology Index (BASMI), Ankylosing Spondylitis Quality of Life (ASQoL) Scale, and adverse events. The methodological quality of the included studies was evaluated using the Cochrane risk of bias (RoB) tool (2.0). The certainty of evidence for each outcome was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria.

resultsOf the 330 studies retrieved, 15 studies satisfied the criteria for meta-analysis. Compared with the controls, MBE interventions significantly improved physical function (measured by BASFI, MD = -0.76, 95% CI: -1.01 to -0.50, P < 0.00001), disease activity (measured by BASDAI, MD = -0.76, 95% CI: -0.94 to -0.57, P < 0.00001), pain intensity (measured by VAS, MD = -0.89, 95% CI: -1.21 to -0.57, P < 0.00001), spinal mobility (measured by BASMI, MD = -0.44, 95% CI: -0.70 to -0.19, P = 0.0006), and quality of life (measured by ASQoL, MD = -2.14, 95% CI: -3.54 to -0.75, P = 0.003). Subgroup analyses revealed that Tai Chi appeared to demonstrate a more pronounced effect on pain reduction when compared to Qigong (test for subgroup difference: P = 0.005). The quality of evidence for these outcomes was estimated as moderate to low. Additionally, no serious adverse events related to MBE were identified among the included studies.

conclusionsOverall, MBE may be a promising non-pharmacological treatment to improve physical function, disease activity, pain intensity, spinal mobility, and quality of life in patients with axSpA. To enhance the certainty of the evidence, additional rigorous studies are needed to verify these findings.

Indexed as

Axial SpondyloarthritisMind-Body TherapiesQuality of LifeExercise TherapyHumansQigongTreatment OutcomeAnkylosing spondylitisAxial spondyloarthritisExerciseMind-body exerciseMind body therapySystematic review

Identifiers

PMID39342350
PMCPMC11438100

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.