Evidence map›Paper›PMID 39344270›Full record

ArticleMagnetic resonance in medicine2025

MRI detection of free-contrast agent nanoparticles.

Francesca Garello, Eleonora Cavallari, Martina Capozza, Marta Ribodino, Roberta Parolisi, Annalisa Buffo, Enzo Terreno

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Bypassing Heteronuclear MRI: Metal-Free Organosilicon Nanotracers for Background-Free HotspotAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. MRI detection of free-contrast agent nanoparticles.Magnetic resonance in medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francesca GarelloMolecular and Preclinical Imaging Centers, Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.ORCID 0000-0002-7150-2003
Eleonora CavallariMolecular and Preclinical Imaging Centers, Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.ORCID 0000-0003-4891-4138
Martina CapozzaMolecular and Preclinical Imaging Centers, Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.
Marta RibodinoDepartment of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy.
Roberta ParolisiDepartment of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy.
Annalisa BuffoDepartment of Neuroscience "Rita Levi Montalcini", University of Turin, Turin, Italy.
Enzo TerrenoMolecular and Preclinical Imaging Centers, Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.

Funding

AIRC IG-22041Associazione Italiana per la Ricerca sul CancroUniversity of Torino
6 · The paper itself

Abstract

purposeThe integration of nanotechnology into biomedical imaging has significantly advanced diagnostic and theranostic capabilities. However, nanoparticle detection in imaging relies on functionalization with appropriate probes. In this work, a new approach to visualize free-label nanoparticles using MRI and MRS techniques is described, consisting of detecting by

methodsThree different nanosystems, namely lipid-based micelles, liposomes, and perfluorocarbon-based nanoemulsions, were synthesized, characterized by high resolution NMR and then visualized by

resultsThe study successfully demonstrates the feasibility of detecting nanoparticles using MRI/MRS without probe functionalization, employing

conclusionsThese findings present a promising avenue for nanoparticle imaging in biomedical applications, offering potential enhancements to diagnostic and theranostic procedures. This non-invasive approach has the capacity to advance imaging techniques and expand the scope of nanoparticle-based biomedical research. Further exploration is necessary to fully explore the implications and applications of this method.

Indexed as

Contrast MediaMagnetic Resonance ImagingNanoparticlesAnimalsCell Line, TumorFemaleFluorocarbonsLiposomesMiceMicellesContrast MediaFluorocarbonsLiposomesMicellesCSIliposomesmicellesMRInanoemulsionsnanoparticles

Identifiers

PMID39344270
PMCPMC11604830

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.