Evidence map›Paper›PMID 39345388›Full record

ArticlebioRxiv : the preprint server for biology2024

Dynamics of microcompartment formation at the mitosis-to-G1 transition.

Viraat Y Goel, Nicholas G Aboreden, James M Jusuf, Haoyue Zhang, Luisa P Mori, Leonid A Mirny, Gerd A Blobel, Edward J Banigan, Anders S Hansen

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Viraat Y GoelDepartment of Biological Engineering, Massachusetts Institute of Technology; Cambridge, MA 02139, USA.ORCID 0000-0002-5532-5756
Nicholas G AboredenPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-4154-048X
James M JusufDepartment of Biological Engineering, Massachusetts Institute of Technology; Cambridge, MA 02139, USA.ORCID 0000-0002-2786-5982
Haoyue ZhangInstitute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China.
Luisa P MoriDivision of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-1050-2931
Leonid A MirnyInstitute for Medical Engineering and Science and Department of Physics, Massachusetts Institute of Technology, Cambridge, 02139 MA, USA.ORCID 0000-0002-0785-5410
Gerd A BlobelPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-0714-9612
Edward J BaniganInstitute for Medical Engineering and Science and Department of Physics, Massachusetts Institute of Technology, Cambridge, 02139 MA, USA.ORCID 0000-0001-5478-7425
Anders S HansenDepartment of Biological Engineering, Massachusetts Institute of Technology; Cambridge, MA 02139, USA.ORCID 0000-0001-7540-7858

Funding

VIRUS PRODUCTION COREP30CA014051 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Jacqueline A. Lees · 1985 to 2026
$93.9M
Center for 3D Structure and Physics of the GenomeUM1HG011536 · NHGRI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DEKKER, JOB, MIRNY, LEONID A · 2020 to 2024
$11.8M
Engineering and Imaging 3D genome structure-function dynamics across time scalesU01DK127405 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI BLOBEL, GERD A, PHILLIPS-CREMINS, JENNIFER ELIZABETH · 2020 to 2024
$5.7M
Graduate Training in Computational and Systems BiologyT32GM087237 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BURGE, CHRISTOPHER B · 2009 to 2023
$4.6M
Resolving transcription factor target search mechanismsR01CA300848 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Anders Sejr Hansen · 2024 to 2026
$2.9M
Polymer models of mitotic and interphase chromosomesR01GM114190 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MIRNY, LEONID A · 2015 to 2023
$2.8M
DYNAMIC BOTTOM-UP DISSECTION OF CHROMATIN LOOPING AND GENE REGULATIONDP2GM140938 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HANSEN, ANDERS SEJR · 2020 to 2020
$2.3M
An integrated toolkit for real-time analysis of coupled nascent transcriptionR01EB035127 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Anders Sejr Hansen · 2024 to 2026
$1.3M
Super-resolution microscopy for dynamic analysis of focal enhancer amplifications in cancerR33CA257878 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HANSEN, ANDERS SEJR · 2021 to 2023
$1.1M
Ultra-high resolution 3D genome maps for multiple human tissuesR03OD038390 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HANSEN, ANDERS SEJR, LIU, JIE · 2024 to 2024
$309k
Investigating the role of Ldb1 in chromatin architecture and transcription during erythroid cell state transitionsF31DK136200 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI ABOREDEN, NICHOLAS · 2024 to 2024
$49k
NCI NIH HHS P30 CA014051NCI NIH HHS R01 CA300848NCI NIH HHS R33 CA257878NHGRI NIH HHS UM1 HG011536NIBIB NIH HHS R01 EB035127NIDDK NIH HHS F31 DK136200NIDDK NIH HHS U01 DK127405NIGMS NIH HHS DP2 GM140938NIGMS NIH HHS R01 GM114190NIGMS NIH HHS T32 GM087237NIH HHS R03 OD038390
6 · The paper itself

Abstract

As cells exit mitosis and enter G1, mitotic chromosomes decompact and transcription is reestablished. Previously, Hi-C studies showed that essentially all interphase 3D genome features including A/B-compartments, TADs, and CTCF loops, are lost during mitosis. However, Hi-C remains insensitive to features such as microcompartments, nested focal interactions between

Identifiers

PMID39345388
PMCPMC11430094

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.