Evidence map›Paper›PMID 39345494›Full record

ArticlebioRxiv : the preprint server for biology2025

Cross-expression meta-analysis of 695 brain samples reveals coordinated gene expression across spatially adjacent cells.

Ameer Sarwar, Mara Rue, Leon French, Helen Cross, Sarah Choi, Xiaoyin Chen, Jesse Gillis

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ameer SarwarDepartment of Cell and Systems Biology and Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-3029-0948
Mara RueAllen Institute for Brain Science, Seattle, WA, USA.
Leon FrenchDepartment of Physiology and Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
Helen CrossAllen Institute for Brain Science, Seattle, WA, USA.
Sarah ChoiDepartment of Physiology and Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
Xiaoyin ChenAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0002-2807-6125
Jesse GillisDepartment of Physiology and Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-0936-9774

Funding

Unraveling the developmental logic of cortical long-range projections using in situ sequencing-based neuroanatomyDP2MH132940 · ALLEN INSTITUTE · 2025 to 2025
$1.1M
Revealing the transcriptional basis of corticothalamic projections using in situ sequence-based neuroanatomyR01MH133181 · ALLEN INSTITUTE · 2025 to 2025
$539k
NIMH NIH HHS DP2 MH132940NIMH NIH HHS R01 MH113005NIMH NIH HHS R01 MH133181
6 · The paper itself

Abstract

Spatial transcriptomics promises to transform our understanding of tissue biology by molecularly profiling individual cells

Indexed as

cell-neighbor relationscross-expressiongene expression coordinationmeta-analytic networkspatial signalingspatial transcriptomics

Identifiers

PMID39345494
PMCPMC11429685

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.