Evidence map›Paper›PMID 39345646›Full record

ArticlebioRxiv : the preprint server for biology2024

Molecular insights into substrate translocation in an elevator-type metal transporter.

Yao Zhang, Majid Jafari, Tuo Zhang, Dexin Sui, Luca Sagresti, Kenneth M Merz, Jian Hu

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yao ZhangDepartment of Biochemistry & Molecular Biology, Michigan State University, MI 48824.
Majid JafariDepartment of Biochemistry & Molecular Biology, Michigan State University, MI 48824.
Tuo ZhangDepartment of Biochemistry & Molecular Biology, Michigan State University, MI 48824.
Dexin SuiDepartment of Biochemistry & Molecular Biology, Michigan State University, MI 48824.
Luca SagrestiScuola Normale Superiore, Piazza dei Cavalieri 7, I-56126 Pisa, Italy and CSGI.
Kenneth M MerzDepartment of Biochemistry & Molecular Biology, Michigan State University, MI 48824.
Jian HuDepartment of Biochemistry & Molecular Biology, Michigan State University, MI 48824.

Funding

Modeling Transition Metal Ion Binding to ProteinsR01GM130641 · NIGMS · MICHIGAN STATE UNIVERSITY · PI KENNETH M. MERZ · 2019 to 2026
$2.5M
Transport, substrate specificity and regulation mechanisms of the ZIP transition metal transportersR35GM140931 · NIGMS · MICHIGAN STATE UNIVERSITY · PI HU, JIAN · 2021 to 2025
$1.7M
Structural and Mechanistic Characterization of the ZIP Metal TransportersR01GM129004 · NIGMS · MICHIGAN STATE UNIVERSITY · PI HU, JIAN · 2018 to 2020
$593k
NIGMS NIH HHS R01 GM129004NIGMS NIH HHS R01 GM130641NIGMS NIH HHS R35 GM140931
6 · The paper itself

Abstract

The Zrt/Irt-like protein (ZIP) metal transporters are key players in maintaining the homeostasis of a panel of essential microelements. The prototypical ZIP from

Indexed as

MetadynamicsMolecular dynamics simulationStructureTransporterTransport mechanismZincZIP

Identifiers

PMID39345646
PMCPMC11429975

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.