Evidence map›Paper›PMID 39349307›Full record

ReviewAJNR. American journal of neuroradiology2025

Mesenchymal Nonmeningothelial Tumors of the CNS: Evolving Molecular Landscape and Implications for Neuroradiologists.

Neetu Soni, Manish Ora, Denes Szekeres, Girish Bathla, Amit Desai, Vivek Gupta, Aparna Singhal, Amit Agarwal

Abstract readReview
In one paragraph

Review in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Non-Meningothelial Mesenchymal Tumor of the Central Nervous System: Case Report and Literature Review.Neuropathology : official journal of the Japanese Society of Neuropathology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Neetu SoniFrom the Department of Radiology (N.S., A.D., V.G., A.A.), Mayo Clinic, Jacksonville, Florida Soni.neetu@mayo.edu.ORCID 0000-0003-2082-1634
Manish OraDepartment of Nuclear Medicine (M.O.), Sanjay Gandhi Post Graduate Institute of Medical Science, Lucknow, India.ORCID 0000-0002-9748-2215
Denes SzekeresUniversity of Rochester (D.S.), School of Medicine and Dentistry, Rochester, New York.
Girish BathlaDepartment of Radiology (G.B.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0003-3170-242X
Amit DesaiFrom the Department of Radiology (N.S., A.D., V.G., A.A.), Mayo Clinic, Jacksonville, Florida.ORCID 0000-0002-3073-6823
Vivek GuptaFrom the Department of Radiology (N.S., A.D., V.G., A.A.), Mayo Clinic, Jacksonville, Florida.ORCID 0000-0002-4298-7179
Aparna SinghalDepartment of Radiology (A.S.), UAB Hospital, Birmingham, Alabama.ORCID 0000-0001-7741-5106
Amit AgarwalFrom the Department of Radiology (N.S., A.D., V.G., A.A.), Mayo Clinic, Jacksonville, Florida.ORCID 0000-0001-9139-8007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization Classification of Tumors of the Central Nervous System, 5th edition (WHO CNS5) significantly revised the terminology and diagnostic criteria of "mesenchymal nonmeningothelial" tumors of CNS to better align with the classification of these soft tissue tumors outside the CNS. The CNS chapter only covers the entities with distinct histologic or molecular characteristics that occur exclusively or primarily in the CNS. These tumors usually arise from the meninges and are rarely intraparenchymal in origin, mainly in the supratentorial compartment. These tumors are grouped into 3 main categories: soft tissue, chondro-osseous, and notochordal. Soft tissue tumors, the largest group, are further divided into fibroblastic, vascular, and skeletal muscle subtypes. Notably, a new subcategory for "tumors of uncertain differentiation" has been introduced, encompassing 3 new histomolecular entities:

Indexed as

Biomarkers, TumorCentral Nervous System NeoplasmsMesenchymomaHumansBiomarkers, Tumor

Identifiers

PMID39349307
PMCPMC12091988

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.