Evidence map›Paper›PMID 39349422›Full record

ArticleCell death & disease2024

CD226 implicated in Akt-dependent apoptosis of CD4

Yuan Zhang, Yang Xie, Xuexin Zhang, Chujun Duan, Jingchang Ma, Yuling Wang, Yilin Wu, Niqi Shan, Kun Cheng, Ran Zhuang and 1 more

Abstract read
In one paragraph

Article in Cell death & disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Abnormal Elevation of the Expression of Costimulatory Molecule CD226 in Graves' DiseaseEndocrine, metabolic & immune disorders drug targets · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuan Zhang *Department of Otolaryngology Head and Neck Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Yang Xie *Department of Otolaryngology Head and Neck Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.ORCID 0000-0003-1875-804X
Xuexin ZhangDepartment of Immunology, Fourth Military Medical University, Xi'an, Shaanxi, China.
Chujun DuanDepartment of Immunology, Fourth Military Medical University, Xi'an, Shaanxi, China.
Jingchang MaDepartment of Immunology, Fourth Military Medical University, Xi'an, Shaanxi, China.
Yuling WangDepartment of Immunology, Fourth Military Medical University, Xi'an, Shaanxi, China.
Yilin WuDepartment of Immunology, Fourth Military Medical University, Xi'an, Shaanxi, China.
Niqi ShanDepartment of Immunology, Fourth Military Medical University, Xi'an, Shaanxi, China.
Kun ChengDepartment of Immunology, Fourth Military Medical University, Xi'an, Shaanxi, China.
Ran ZhuangDepartment of Immunology, Fourth Military Medical University, Xi'an, Shaanxi, China. fmmuzhr@fmmu.edu.cn.ORCID 0000-0002-3614-0422
Ka BianDepartment of Otolaryngology Head and Neck Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China. kabian@fmmu.edu.cn.ORCID 0000-0002-5190-1074

Funding

National Natural Science Foundation of China (National Science Foundation of China) 81871258
6 · The paper itself

Abstract

Asthma is a chronic airway inflammatory disease in which CD4

Indexed as

Antigens, Differentiation, T-LymphocyteApoptosisAsthmaCD4-Positive T-LymphocytesMice, KnockoutProto-Oncogene Proteins c-aktAdultAnimalsDisease Models, AnimalFemaleHumansMaleMiceMice, Inbred C57BLSignal TransductionT Lineage-Specific Activation Antigen 1Antigens, Differentiation, T-LymphocyteProto-Oncogene Proteins c-aktT Lineage-Specific Activation Antigen 1

Identifiers

PMID39349422
PMCPMC11442704

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.