Evidence mapPaperPMID 39349441Full record

ArticleNature communications2024

Air pollution below US regulatory standards and cardiovascular diseases using a double negative control approach.

Yichen Wang, Mahdieh Danesh Yazdi, Yaguang Wei, Joel D Schwartz

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Long-term exposure to PMEnvironmental research · 2025
    Article
  5. Article
  6. Article
  7. Exposure to low concentrations of PMBMC public health · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Yichen WangDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA. yichen.wang.yw@yale.edu.
Mahdieh Danesh YazdiProgram in Public Health, Department of Family, Population, & Preventive Medicine, Stony Brook University, Stony Brook, NY, USA.
Yaguang WeiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-6796-7510
Joel D SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0001-6168-378X

Funding

TOXICOLOGYP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Douglas W Dockery · 1985 to 2023
$12.4M
Identifying low dose measurement error corrected effects of multiple pollutants using causal modelingR01ES032418 · NIEHS · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Joel D Schwartz · 2022 to 2024
$1.0M
EPA R835872NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES032418U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01 ES032418-01
6 · The paper itself

Abstract

Growing evidence suggests that long-term air pollution exposure is a risk factor for cardiovascular mortality and morbidity. However, few studies have investigated air pollution below current regulatory limits, and causal evidence is limited. We use a double negative control approach to examine the association between long-term exposure to air pollution at low concentration and cardiovascular hospitalizations among US Medicare beneficiaries aged ≥65 years between 2000 and 2016. The expected values of the negative outcome control (preceding-year hospitalizations) regressed on exposure and negative exposure control (subsequent-year exposure) are treated as a surrogate for omitted confounders. With analyses separately restricted to low-pollution areas (PM

Indexed as

Air PollutantsAir PollutionCardiovascular DiseasesHospitalizationParticulate MatterAgedAged, 80 and overEnvironmental ExposureFemaleHumansMaleMedicareOzoneRisk FactorsUnited StatesAir PollutantsOzoneParticulate Matter

Identifiers

PMID39349441
PMCPMC11444044

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.