ArticleNature biomedical engineering2025
A fast all-optical 3D photoacoustic scanner for clinical vascular imaging.
Article in Nature biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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The trial behind it
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Who cites it
45 citing papers in PubMed.
- Activatable NIR-II photoacoustic probes for cancer imaging and imaging-guided therapy.Bioactive materials · 2026Review
- Photoacoustic and ultrasound Imaging of placental functions in gestational diabetes: From diagnosis to precision interventions.Photoacoustics · 2026Review
- Optimization of light source parameters for photoacoustic imaging: trade-offs, technologies, and clinical considerations.JPhys photonics · 2026Review
- Photoacoustic Imaging in Immune-Mediated Inflammatory Skin Diseases: Diagnostic and Therapeutic Applications.Diagnostics (Basel, Switzerland) · 2026Review
- Mapping blood vessels and oxygenation throughout the whole mouse brain with dual-frequency fiber-array photoacoustic computed tomography.Light, science & applications · 2026Article
- Panoramic Near-Infrared Imaging Device for Peripheral Vascular Mapping.Sensors (Basel, Switzerland) · 2026Article
- Ultra-sensitive wideband diffraction-grating-coupled-mode Fabry-Pérot resonators for ultrasound and photoacoustic detection.Photoacoustics · 2026Article
- Robust hybrid feature-driven on-the-fly mapping enables freehand 3D panoramic photoacoustic angiography.Light, science & applications · 2026Article
- In Vivo Microplastic Detection With Photoacoustic Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Smartphone-Based Blood Pressure Monitoring via the Oscillometric Finger Pressing Method: Investigation of the DC Component of PPG.IEEE transactions on bio-medical engineering · 2026Article
- Three-dimensional aperture-driven photoacoustic tomography (3D-ADPAT).Science advances · 2026Article
- Investigating Age-Dependent Oxygenation and Blood Perfusion in a Mouse Model of Peripheral Artery Disease (PAD) Using Multispectral Optoacoustic Tomography (MSOT), Laser Speckle Contrast Imaging (LSCI) and Histology.Diagnostics (Basel, Switzerland) · 2026Article
- Data-driven super-resolution optoacoustic imaging via physically encoded signal acquisition.Research square · 2026Article
- Multiple reflection: A Route to enhanced sensitivity in beam-deflection optical ultrasound sensing.Photoacoustics · 2026Article
- Ultrasound-Based Techniques for Visualization of Dermal Microvasculature: A Scoping Review.Diagnostics (Basel, Switzerland) · 2026Review
- Deep computational photoacoustic mesoscopy through heterogeneous tissues enabled by scanning compensation and angular-spectrum enhancement.Photoacoustics · 2026Article
- Real-Time and High-Resolution NIR-II-L Imaging of Netrin-1-Mediated Neurovascular Coupling Driven by Dose-Dependent Electroacupuncture.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Efficient denoising in LED-based optoacoustic tomography with squeeze-and-excitation deep convolutional networks.Journal of biomedical optics · 2026Article
- Photoacoustic Noninvasive Blood Glucose Monitoring: A Review of Systems and Strategies for Robust Glucose Concentration Estimation, with Perspectives on Miniaturization and Wearability.Sensors (Basel, Switzerland) · 2026Review
- Feasibility of 3D photoacoustic tomography for the assessment of rheumatoid arthritis.The British journal of radiology · 2026Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
The clinical assessment of microvascular pathologies (in diabetes and in inflammatory skin diseases, for example) requires the visualization of superficial vascular anatomy. Photoacoustic tomography (PAT) scanners based on an all-optical Fabry-Perot ultrasound sensor can provide highly detailed 3D microvascular images, but minutes-long acquisition times have precluded their clinical use. Here we show that scan times can be reduced to a few seconds and even hundreds of milliseconds by parallelizing the optical architecture of the sensor readout, by using excitation lasers with high pulse-repetition frequencies and by exploiting compressed sensing. A PAT scanner with such fast acquisition minimizes motion-related artefacts and allows for the volumetric visualization of individual arterioles, venules, venous valves and millimetre-scale arteries and veins to depths approaching 15 mm, as well as for dynamic 3D images of time-varying tissue perfusion and other haemodynamic events. In exploratory case studies, we used the scanner to visualize and quantify microvascular changes associated with peripheral vascular disease, skin inflammation and rheumatoid arthritis. Fast all-optical PAT may prove useful in cardiovascular medicine, oncology, dermatology and rheumatology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.