ArticleCommunications biology2024
Dynamical structure-function correlations provide robust and generalizable signatures of consciousness in humans.
Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed.
- Differential Dynamic Reorganization of Functional Connectivity Based on Phase Synchrony and Amplitude Envelope Coupling During Propofol Sedation.Brain sciences · 2026Article
- Reorganization of Human Brain Waves Across Diverse States of Consciousness.bioRxiv : the preprint server for biology · 2026Article
- AI-Resolved Protein Energy Landscapes, Electrodynamics, and Fluidic Microcircuits as a Unified Framework for Predicting Neurodegeneration.International journal of molecular sciences · 2026Review
- THOI: An efficient and accessible library for computing higher-order interactions enhanced by batch-processing.PloS one · 2026Article
- Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness.eLife · 2025Article
- Changes in brain connectivity and neurovascular dynamics during dexmedetomidine-induced loss of consciousness.Communications biology · 2025Article
- Brain sources composing irregular field potentials have unique temporal signatures.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- A computational approach to evaluate how molecular mechanisms impact large-scale brain activity.Nature computational science · 2025Article
- DySCo: A general framework for dynamic functional connectivity.PLoS computational biology · 2025Article
- Entropy and Complexity Tools Across Scales in Neuroscience: A Review.Entropy (Basel, Switzerland) · 2025Review
- Graph models of brain state in deep anesthesia reveal sink state dynamics of reduced spatiotemporal complexity.Network neuroscience (Cambridge, Mass.) · 2025Article
- Transcranial ultrasound stimulation effect in the redundant and synergistic networks consistent across macaques.Network neuroscience (Cambridge, Mass.) · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resting-state functional magnetic resonance imaging evolves through a repertoire of functional connectivity patterns which might reflect ongoing cognition, as well as the contents of conscious awareness. We investigated whether the dynamic exploration of these states can provide robust and generalizable markers for the state of consciousness in human participants, across loss of consciousness induced by general anaesthesia or slow wave sleep. By clustering transient states of functional connectivity, we demonstrated that brain activity during unconsciousness is dominated by a recurrent pattern primarily mediated by structural connectivity and with a reduced capacity to transition to other patterns. Our results provide evidence supporting the pronounced differences between conscious and unconscious brain states in terms of whole-brain dynamics; in particular, the maintenance of rich brain dynamics measured by entropy is a critical aspect of conscious awareness. Collectively, our results may have significant implications for our understanding of consciousness and the neural basis of human awareness, as well as for the discovery of robust signatures of consciousness that are generalizable among different brain conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.