Evidence map›Paper›PMID 39349661›Full record

ReviewPediatric radiology2024

Pre-clinical and clinical trials for anesthesia in neonates: gaps and future directions.

Katherine Barton, R Dexter Yellowman, Tara Holm, Forrest Beaulieu, Gabriel Zuckerberg, Kriti Gwal, Bindu N Setty, Emily Janitz, Misun Hwang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katherine BartonDepartment of Radiology, Oregon Health & Science University, Portland, OR, USA. barton.katherine@gmail.com.ORCID 0000-0002-8597-1978
R Dexter YellowmanUniversity of Minnesota Medical School, Minneapolis, MN, USA.
Tara HolmDepartment of Radiology, University of Minnesota, Masonic Children's Hospital, Minneapolis, MN, USA.
Forrest BeaulieuDepartment of Anesthesia and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Gabriel ZuckerbergDepartment of Anesthesia and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kriti GwalDepartment of Radiology, Nemours Children's Hospital, Wilmington, DE, USA.
Bindu N SettyDepartment of Radiology, Boston University, Boston, MA, USA.
Emily JanitzDepartment of Radiology, Akron Children's Hospital, Akron, OH, USA.
Misun HwangDepartment of Radiology, University of Pennsylvania, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Literature examining possible deleterious effects of anesthesia exposure on the developing brain has increased substantially over the past 30 years. Initial concerning findings in animal models, both rodents and non-human primates, prompted increasingly thorough examinations in humans, including randomized controlled trials. This review will provide a concise overview of what we know about anesthesia and the developing brain: the background in animal studies, the most robust results we have in humans, and the work yet to be done. This is particularly relevant to a pediatric radiology audience because we have the unique opportunity to modify anesthesia exposure during imaging through innovation.

Indexed as

AnesthesiaAnimalsBrainClinical Trials as TopicForecastingHumansInfant, NewbornAnesthesiaAnimals, newbornChild developmentDrug toxicityInfantNewborn

Identifiers

PMID39349661

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.