Evidence map›Paper›PMID 39350240›Full record

ReviewEye and vision (London, England)2024

Advances and prospects of multi-modal ophthalmic artificial intelligence based on deep learning: a review.

Shaopan Wang, Xin He, Zhongquan Jian, Jie Li, Changsheng Xu, Yuguang Chen, Yuwen Liu, Han Chen, Caihong Huang, Jiaoyue Hu and 1 more

Abstract readReview
In one paragraph

Review in Eye and vision (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. AI-driven multimodal retinal imaging for early detection and risk stratification of vascular and neurodegenerative diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  3. Surgical outcomes and risk factors identification for rhegmatogenous retinal detachment repair by pneumatic retinopexy using pure air.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  4. Toward comprehensive real-time scene understanding in ophthalmic surgery through multimodal image fusion.International journal of computer assisted radiology and surgery · 2026
    Article
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  18. Artificial intelligence in ophthalmology: opportunities, challenges, and ethical considerations.Medical hypothesis, discovery & innovation ophthalmology journal · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shaopan Wang *Institute of Artificial Intelligence, Xiamen University, Xiamen, Fujian, China.ORCID http://orcid.org/0000-0001-8044-8398
Xin He *Xiamen University Affiliated Xiamen Eye Center, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Fujian Engineering and Research Center of Eye Regenerative Medicine, Eye Institute of Xiamen University, School of Medicine, Xiamen University, Chengyi Building, 4Th Floor, 4221-122, South Xiang'an Rd, Xiamen, 361005, Fujian, China.
Zhongquan JianInstitute of Artificial Intelligence, Xiamen University, Xiamen, Fujian, China.
Jie LiNational Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Changsheng XuInstitute of Artificial Intelligence, Xiamen University, Xiamen, Fujian, China.
Yuguang ChenInstitute of Artificial Intelligence, Xiamen University, Xiamen, Fujian, China.
Yuwen LiuXiamen University Affiliated Xiamen Eye Center, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Fujian Engineering and Research Center of Eye Regenerative Medicine, Eye Institute of Xiamen University, School of Medicine, Xiamen University, Chengyi Building, 4Th Floor, 4221-122, South Xiang'an Rd, Xiamen, 361005, Fujian, China.
Han ChenDepartment of Ophthalmology, the First Affiliated Hospital of Xiamen University, Xiamen University, Xiamen, Fujian, China.
Caihong HuangXiamen University Affiliated Xiamen Eye Center, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Fujian Engineering and Research Center of Eye Regenerative Medicine, Eye Institute of Xiamen University, School of Medicine, Xiamen University, Chengyi Building, 4Th Floor, 4221-122, South Xiang'an Rd, Xiamen, 361005, Fujian, China.
Jiaoyue HuXiamen University Affiliated Xiamen Eye Center, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Fujian Engineering and Research Center of Eye Regenerative Medicine, Eye Institute of Xiamen University, School of Medicine, Xiamen University, Chengyi Building, 4Th Floor, 4221-122, South Xiang'an Rd, Xiamen, 361005, Fujian, China. mydear_22000@163.com.
Zuguo LiuInstitute of Artificial Intelligence, Xiamen University, Xiamen, Fujian, China. zuguoliu@xmu.edu.cn.

Funding

National Natural Science Foundation of China 82201149National Natural Science Foundation of China 82271054National Natural Science Foundation of China U20A20363
6 · The paper itself

Abstract

backgroundIn recent years, ophthalmology has emerged as a new frontier in medical artificial intelligence (AI) with multi-modal AI in ophthalmology garnering significant attention across interdisciplinary research. This integration of various types and data models holds paramount importance as it enables the provision of detailed and precise information for diagnosing eye and vision diseases. By leveraging multi-modal ophthalmology AI techniques, clinicians can enhance the accuracy and efficiency of diagnoses, and thus reduce the risks associated with misdiagnosis and oversight while also enabling more precise management of eye and vision health. However, the widespread adoption of multi-modal ophthalmology poses significant challenges. MAIN TEXT: In this review, we first summarize comprehensively the concept of modalities in the field of ophthalmology, the forms of fusion between modalities, and the progress of multi-modal ophthalmic AI technology. Finally, we discuss the challenges of current multi-modal AI technology applications in ophthalmology and future feasible research directions.

conclusionIn the field of ophthalmic AI, evidence suggests that when utilizing multi-modal data, deep learning-based multi-modal AI technology exhibits excellent diagnostic efficacy in assisting the diagnosis of various ophthalmic diseases. Particularly, in the current era marked by the proliferation of large-scale models, multi-modal techniques represent the most promising and advantageous solution for addressing the diagnosis of various ophthalmic diseases from a comprehensive perspective. However, it must be acknowledged that there are still numerous challenges associated with the application of multi-modal techniques in ophthalmic AI before they can be effectively employed in the clinical setting.

Indexed as

Artificial intelligenceDeep learningMulti-modal ophthalmic research

Identifiers

PMID39350240
PMCPMC11443922

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.