Evidence mapPaperPMID 39350296Full record

ReviewVirology journal2024

Advances in nucleic acid aptamer-based detection of respiratory virus and bacteria: a mini review.

Rui-Min Feng, Ye Liu, Zhi-Qiang Liu, Li Wang, Nan Chen, Yu Zhao, Hua-Wei Yi

Abstract readReview
In one paragraph

Review in Virology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rui-Min FengLaboratory Department, the First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, People's Republic of China.
Ye LiuLaboratory Department, the First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, People's Republic of China.
Zhi-Qiang LiuCentral Laboratory, the First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, People's Republic of China.
Li WangLaboratory Department, the First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, People's Republic of China.
Nan ChenHealth Science Center, Yangtze University, Jingzhou, Hubei, People's Republic of China.
Yu ZhaoOncology Department, the First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, People's Republic of China. 1458666138@qq.com.
Hua-Wei YiLaboratory Department, the First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, People's Republic of China. yihuawei0902@126.com.

Funding

The Doctoral Research Start-up Fund Project of the First People's Hospital of Jingzhou, China 2023DIF03
6 · The paper itself

Abstract

Respiratory pathogens infecting the human respiratory system are characterized by their diversity, high infectivity, rapid transmission, and acute onset. Traditional detection methods are time-consuming, have low sensitivity, and lack specificity, failing to meet the needs of rapid clinical diagnosis. Nucleic acid aptamers, as an emerging and innovative detection technology, offer novel solutions with high specificity, affinity, and broad target applicability, making them particularly promising for respiratory pathogen detection. This review highlights the progress in the research and application of nucleic acid aptamers for detecting respiratory pathogens, discussing their selection, application, potential in clinical diagnosis, and future development. Notably, these aptamers can significantly enhance the sensitivity and specificity of detection when combined with detection techniques such as fluorescence, colorimetry and electrochemistry. This review offers new insights into how aptamers can address the limitations of traditional diagnostic methods and advance clinical diagnostics. It also highlights key challenges and future research directions for the clinical application of nucleic acid aptamers.

Indexed as

Aptamers, NucleotideRespiratory Tract InfectionsSensitivity and SpecificityBacteriaHumansMolecular Diagnostic TechniquesSELEX Aptamer TechniqueVirus DiseasesVirusesAptamers, NucleotideClinical diagnosisNucleic acid aptamersPathogen detectionRespiratory pathogensSELEX

Identifiers

PMID39350296
PMCPMC11443872

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.