Evidence map›Paper›PMID 39350356›Full record

Trial reportJournal of cardiovascular electrophysiology2024

Body mass index as a determinant of scar formation post-AF ablation: Insights from DECAAF II.

Ghassan Bidaoui, Eli Tsakiris, Hadi Younes, Han Feng, Ala Assaf, Nour Chouman, Mayana Bsoul, Francisco Tirado Polo, Yishi Jia, Yingshou Liu and 9 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cardiovascular electrophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ghassan BidaouiTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0002-3562-7386
Eli TsakirisTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0009-0003-2542-941X
Hadi YounesTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0002-7202-1164
Han FengTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Ala AssafTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Nour ChoumanTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Mayana BsoulTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Francisco Tirado PoloTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Yishi JiaTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Yingshou LiuTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Chanho LimTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Nadia ChamounTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Mario MekhaelTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0001-8809-5419
Charbel NoujaimTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Amitabh C PandeyTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Swati RaoTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Omar KreidiehTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0001-6189-2821
Nassir F MarroucheTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0003-0454-0541
Eoin DonnellanTulane Research Innovation for Arrhythmia Discovery (TRIAD), Cardiac Electrophysiology, Tulane University School of Medicine, New Orleans, Louisiana, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionObesity is implicated in adverse atrial remodeling and worse outcomes in patients with atrial fibrillation. The objective of this study is to assess the effect of body mass index (BMI) on ablation-induced scar formation on late gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMR).

methodsWe conducted an analysis of DECAAF II participants who underwent LGE-CMR scans to measure scar formation 3 months after catheter ablation. Ablation parameters and lesion delivery were not dependent on BMI. The effect of BMI on ablation success was explored.

resultsOur analyses included 811 patients. Comorbidities were more prevalent in obese patients. Baseline left atrial volume was higher in obese individuals, 118, 126, 135, 140, and 143 mm

conclusionObese patients have lower ablation scar formation, covered fibrosis, and more residual fibrosis postablation compared to nonobese patients, regardless of ablation parameters including impedance drop.

Indexed as

Atrial FibrillationBody Mass IndexCatheter AblationCicatrixFibrosisObesityAgedAtrial RemodelingFemaleHeart RateHumansMaleMiddle AgedPredictive Value of TestsRisk AssessmentRisk Factorsatrial fibrillationatrial remodelingcatheter ablationobesityscar formation

Identifiers

PMID39350356
PMCPMC11650536

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.