Evidence map›Paper›PMID 39350419›Full record

ReviewPharmaceutical nanotechnology2026

Therapeutic and Diagnostic Implications of Carbon Dot: An Advancement in the Avenue towards Cancer, Diabetes and Neurodegenerative Disorders.

Sreejan Manna, Sabyasachi Banerjee, Arnab De, Subhasis Banerjee, Stabak Das, Pallabita Rakshit, Ashok Kumar S K, Kalyan Kumar Sen, Sourav De

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pharmaceutical nanotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sreejan MannaDepartment of Pharmaceutical Technology, Brainware University, Barasat, Kolkata, West Bengal, 700125, India.
Sabyasachi BanerjeeDepartment of Pharmaceutical Chemistry, Gupta College of Technological Sciences. Asansol, 713301, West Bengal, India.
Arnab DeDepartment of Pharmaceutics, Bharat Technology, Uluberia, Howrah, 711316, India.
Subhasis BanerjeeDepartment of Pharmaceutical Chemistry, Gupta College of Technological Sciences. Asansol, 713301, West Bengal, India.
Stabak DasDepartment of Pharmaceutical Technology, Brainware University, Barasat, Kolkata, West Bengal, 700125, India.
Pallabita RakshitDepartment of Pharmaceutical Technology, Jadavpur University, Kolkata, 700032, India.
Ashok Kumar S KDepartment of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, 632014, Tamil Nadu, India.
Kalyan Kumar SenDepartment of Pharmaceutical Chemistry, Gupta College of Technological Sciences. Asansol, 713301, West Bengal, India.
Sourav DeDepartment of Pharmaceutical Technology, Eminent College of Pharmaceutical Technology, Kolkata, 700126, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCarbon dots (CDs), by virtue of their electrical and optical properties, emit intense light and fluorescence. They have attributes like photostability, high quantum yield (QY), high emission, and scalability. In the recent past, theranostic-CDs have been widely used in sensing, imaging, and medication administration. Furthermore, CDs may provide significant promise to detect and ability to cros blood-brain barrier (BBB) along with a drug to treat numerous neurodegenerative disorders (ND), such as Parkinson's disease (PD), Alzheimer's disease (AD), and multiple scleross.

methodsThis review aims at exploring the immense utility of CDs in the arena of theranostics. The immense utility of CDs was investigated through a systematic exploration of previously published data in the relevant field. The application of CDs is well extended to treat life-threatening disorders, like diabetes and cancer. In order to keep harmful substances out of the brain, the blood- -brain barrier (BBB) forms a defensive barrier.

resultsWater and gases being simple molecules can traverse the BBB without getting filtered out, but several large molecules suffer to reach the site of action owing to their poor solubility. CDs have recently been employed for delivering drugs to the brain and to assess the central nervous system. An in-depth study of relevant literature indicates that CDs are the next-generation carrier with an innate potential to subside the drawbacks of conventional nanoparticles. DISCUSSION: CDs have recently been employed for delivering drugs to the brain and to assess the central nervous system. An in-depth study of relevant literature indicates that CDs are the next-- generation carrier with an innate potential to subside the drawbacks of conventional nanoparticles.

conclusionThis review illustrates several biomedical applications of CDs, primarily focusing on neurological illnesses, diabetes, and cancers. It also confers the usefulness of CDs in diagnostic imaging.

Indexed as

CarbonDiabetes MellitusNeoplasmsNeurodegenerative DiseasesQuantum DotsAnimalsBlood-Brain BarrierHumansTheranostic NanomedicineCarbonAlzheimer's diseaseblood-brain barrier.cancerCarbon dotsdiabetesParkinson’s disease

Identifiers

PMID39350419

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.