Evidence map›Paper›PMID 39351240›Full record

ReviewFrontiers in immunology2024

Strategies for developing self-assembled nanoparticle vaccines against SARS-CoV-2 infection.

Kaiwen Yang, Youqin Zeng, Xinyu Wu, Jia Li, Jinlin Guo

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kaiwen YangCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Youqin ZengCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xinyu WuCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jia LiCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jinlin GuoCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the recent history of the SARS-CoV-2 outbreak, vaccines have been a crucial public health tool, playing a significant role in effectively preventing infections. However, improving the efficacy while minimizing side effects remains a major challenge. In recent years, there has been growing interest in nanoparticle-based delivery systems aimed at improving antigen delivery efficiency and immunogenicity. Among these, self-assembled nanoparticles with varying sizes, shapes, and surface properties have garnered considerable attention. This paper reviews the latest advancements in the design and development of SARS-CoV-2 vaccines utilizing self-assembled materials, highlighting their advantages in delivering viral immunogens. In addition, we briefly discuss strategies for designing a broad-spectrum universal vaccine, which provides insights and ideas for dealing with possible future infectious sarbecoviruses.

Indexed as

COVID-19COVID-19 VaccinesNanoparticlesAnimalsHumansNanovaccinesVaccine DevelopmentCOVID-19 VaccinesNanovaccinesferritinSARS-CoV-2self-assembled nanoparticlevaccineVLP

Identifiers

PMID39351240
PMCPMC11440195

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.