Evidence map›Paper›PMID 39352495›Full record

ArticleChemical communications (Cambridge, England)2024

Fluorine-18 incorporation and radiometal coordination in macropa ligands for PET imaging and targeted alpha therapy.

Thines Kanagasundaram, Yang Sun, Kevin K Lee, Samantha N MacMillan, Pedro Brugarolas, Justin J Wilson

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thines KanagasundaramDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY-14853, USA.
Yang SunDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA-02114, USA. pbrugarolas@mgh.harvard.edu.ORCID http://orcid.org/0000-0001-6728-4923
Kevin K LeeDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY-14853, USA.ORCID http://orcid.org/0000-0002-1510-0237
Samantha N MacMillanDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY-14853, USA.ORCID http://orcid.org/0000-0001-6516-1823
Pedro BrugarolasDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA-02114, USA. pbrugarolas@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-7455-2743
Justin J WilsonDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY-14853, USA.ORCID http://orcid.org/0000-0002-4086-7982

Funding

Chelators to Enable Theranostic Alpha Particle Radiotherapeutic AgentsR56EB029259 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI WILSON, JUSTIN J · 2024 to 2024
$532k
NIBIB NIH HHS R56 EB029259
6 · The paper itself

Abstract

The development of theranostic agents for radiopharmaceuticals based on therapeutic alpha emitters marks an important clinical need. We describe a strategy for the development of theranostic agents of this type

Indexed as

BismuthFluorine RadioisotopesPositron-Emission TomographyRadiopharmaceuticalsAlpha ParticlesChelating AgentsCoordination ComplexesHumansLeadLigandsMacrocyclic CompoundsBismuthChelating AgentsCoordination ComplexesFluorine-18Fluorine RadioisotopesLeadLigandsMacrocyclic CompoundsRadiopharmaceuticals

Identifiers

PMID39352495
PMCPMC11649299

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.