Evidence map›Paper›PMID 39352759›Full record

ArticleJournal of the American Society of Nephrology : JASN2025

Natural History and Clinicopathological Associations of TRPC6-Associated Podocytopathy.

Benjamin Wooden, Andrew Beenken, Elena Martinelli, Ken Saida, Andrea L Knob, Juntao Ke, Isabella Pisani, Gina Jin, Brandon Lane, Adele Mitrotti and 40 more

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Elucidating Therapeutic Targets in Hereditary Multicentric Carpotarsal Osteolysis FSGS.Journal of the American Society of Nephrology : JASN · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Fifty Shades of Risk: Population Studies and the Genetic Architecture of Kidney Diseases.Journal of the American Society of Nephrology : JASN · 2026
    Review
  6. Article
  7. Genotype-phenotype correlations and clinical outcomes of genetic TRPC6 podocytopathies.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Observational
  8. Podocytopathies.Nature reviews. Disease primers · 2025
    Review
  9. Review
  10. Article
  11. Genotype-Phenotype Correlations with TRPC6-Associated Podocytopathy.Journal of the American Society of Nephrology : JASN · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

Benjamin WoodenDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0003-4286-5005
Andrew BeenkenDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0003-1166-6716
Elena MartinelliDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0009-0004-3983-1116
Ken SaidaDivision of Pediatric Nephrology, Boston Children's Hospital, Boston, Massachusetts.ORCID 0000-0002-4686-6147
Andrea L KnobNephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Juntao KeDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0003-2948-9359
Isabella PisaniDipartimento di Medicina e Chirurgia, Università di Parma, Unità Operativa Nefrologia, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.ORCID 0000-0002-7770-2647
Gina JinDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.
Brandon LaneDivision of Nephrology, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0002-1158-1117
Adele MitrottiSection of Nephrology, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.ORCID 0000-0002-7037-7773
Elizabeth ColbyDepartment of Pediatric Nephrology, Bristol Renal and Royal Bristol Children Hospital, University of Bristol, Bristol, United Kingdom.
Tze Y LimDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.
Francesca GuglielmiDipartimento di Medicina e Chirurgia, Università di Parma, Unità Operativa Nefrologia, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.ORCID 0000-0001-9619-9613
Amy J OsborneDepartment of Pediatric Nephrology, Bristol Renal and Royal Bristol Children Hospital, University of Bristol, Bristol, United Kingdom.ORCID 0000-0001-6869-1176
Dina F AhramDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0003-4617-3938
Chen WangDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0001-9127-0054
Farid ArmandDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0001-8079-1786
Francesca ZanoniDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0001-9567-6713
Andrew S BombackDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0001-5449-1667
Marco DelsanteDipartimento di Medicina e Chirurgia, Università di Parma, Unità Operativa Nefrologia, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.ORCID 0000-0003-0715-6764
Gerald B AppelDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0009-0009-4260-6143
Massimo R A FerrariDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0009-0006-4667-7131
Jeremiah MartinoDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0001-8398-2801
Sunil SahdeoActio Biosciences Inc., San Diego, California.ORCID 0000-0001-6355-0163
David BreckenridgeActio Biosciences Inc., San Diego, California.ORCID 0000-0002-8975-4284
Slavé PetrovskiCentre for Genomics Research, Discovery Sciences, BioPharmaceuticals R D, AstraZeneca, Cambridge, United Kingdom.ORCID 0000-0002-1527-961
Dirk S PaulCentre for Genomics Research, Discovery Sciences, BioPharmaceuticals R D, AstraZeneca, Cambridge, United Kingdom.ORCID 0000-0002-8230-0116
Gentzon HallDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Riccardo MagistroniSection of Nephrology, Surgical, Medical and Dental Department of Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-3319-0248
Corrado MurtasDivision of Nephrology and Dialysis, Belcolle Hospital, Viterbo, Italy.ORCID 0000-0001-7801-6596
Sandro FeriozziDivision of Nephrology and Dialysis, Belcolle Hospital, Viterbo, Italy.
Teresa RampinoUnit of Nephrology, Department of Internal Medicine, Pavia University, Dialysis and Transplantation Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Pasquale EspositoDepartment of Internal Medicine and Medical Specialties (DIMI), University of Genoa, Genoa, Italy.ORCID 0000-0002-0834-5586
Margaret E HelmuthDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-3311-3223
Matthew G SampsonDivision of Pediatric Nephrology, Boston Children's Hospital, Boston, Massachusetts.
Matthias KretzlerDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-4064-0582
Krzysztof KirylukDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0002-5047-6715
Shirlee ShrilDivision of Pediatric Nephrology, Boston Children's Hospital, Boston, Massachusetts.
Loreto GesualdoSection of Nephrology, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.ORCID 0000-0002-4861-0911
Umberto MaggioreDipartimento di Medicina e Chirurgia, Università di Parma, Unità Operativa Nefrologia, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.ORCID 0000-0002-7468-9600
Enrico FiaccadoriDipartimento di Medicina e Chirurgia, Università di Parma, Unità Operativa Nefrologia, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.ORCID 0000-0002-6532-7675
Rasheed GbadegesinDivision of Nephrology, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0001-5641-6644
Dominick SantorielloThe Renal Pathology Laboratory of the Department of Pathology and Cell Biology, Columbia University, New York, New York.
Vivette D D'AgatiThe Renal Pathology Laboratory of the Department of Pathology and Cell Biology, Columbia University, New York, New York.ORCID 0000-0001-7760-6965
Moin A SaleemDepartment of Pediatric Nephrology, Bristol Renal and Royal Bristol Children Hospital, University of Bristol, Bristol, United Kingdom.ORCID 0000-0002-9808-4518
Ali G GharaviDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0003-2801-233
Friedhelm HildebrandtDipartimento di Medicina e Chirurgia, Università di Parma, Unità Operativa Nefrologia, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.ORCID 0000-0002-7130-0030
Martin R PollakNephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
David B GoldsteinActio Biosciences Inc., San Diego, California.
Simone Sanna-CherchiDivision of Nephrology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.ORCID 0000-0002-6185-948

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
OMOP information model for eMERGE phenotypingU01HG008680 · NHGRI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Wendy K Chung, GEORGE M HRIPCSAK · 2015 to 2026
$13.3M
The Columbia PCC for CureGN: the Cure Glomerulonephropathy networkU01DK100876 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Andrew Stephen Bomback, ALI G GHARAVI · 2019 to 2026
$8.5M
Integrating large scale genomics and functional studies to accelerate FSGS/NS discoveryRC2DK122397 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI HILDEBRANDT, FRIEDHELM, POLLAK, MARTIN R. · 2020 to 2024
$7.4M
Identification and function of new genes causing childhood nephrotic syndromeR01DK076683 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HILDEBRANDT, FRIEDHELM · 2007 to 2021
$5.3M
Genomics of glomerular diseaseRC2DK116690 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KIRYLUK, KRZYSZTOF, KRETZLER, MATTHIAS · 2018 to 2022
$5.0M
Genetics of IgA nephropathy by integrative network-based association studiesR01DK105124 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Krzysztof Kiryluk · 2015 to 2026
$4.8M
Non-APOL1 genetic factors and kidney transplant outcomesR01DK136765 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Krzysztof Kiryluk · 2023 to 2026
$2.9M
MHC and KIR Sequencing and Association Analyses in the iGeneTRAiN StudiesU01AI152960 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI KAMOUN, MALEK, KEATING, BRENDAN JAMES · 2020 to 2024
$2.8M
Deep learning based predictive analytics to improve patient health.R01LM013061 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Krzysztof Kiryluk, CHUNHUA WENG · 2019 to 2026
$2.7M
REGULATORS OF CALCINEURIN PATHWAYS AS DIAGNOSTIC AND THERAPEUTIC TARGETS FOR NEPHROTIC SYNDROMER01DK134347 · NIDDK · DUKE UNIVERSITY · PI Rasheed Adebayo Gbadegesin · 2023 to 2026
$2.6M
The Role of Interleukin-15 Receptor-alpha Variants in the Pathogenesis of FSGSK08DK111940 · NIDDK · DUKE UNIVERSITY · PI HALL, GENTZON · 2017 to 2021
$794k
DOD W81XWH2110550National Center for Advancing Translational Sciences, National Institutes of Health UL1TR001873National Institute of Health R01-DK007092National Institute of Health RC2-DK116690National Institute of Health RC2-DK122397NCATS NIH HHS UL1 TR001873NHGRI NIH HHS U01 HG008680NIAID NIH HHS U01 AI152960NICHD NIH HHS R21 HD104176NIDDK NIH HHS 1U01-DK100876NIDDK NIH HHS DK122397NIDDK NIH HHS K08 DK111940NIDDK NIH HHS K08-DK111940NIDDK NIH HHS K08 DK132511NIDDK NIH HHS K08-DK132511NIDDK NIH HHS R01 DK076683NIDDK NIH HHS R01 DK105124NIDDK NIH HHS R01 DK134347NIDDK NIH HHS R01 DK136765NIDDK NIH HHS RC2 DK116690NIDDK NIH HHS RC2 DK122397NIDDK NIH HHS U01 DK100876NIH HHS 1R01-DK134347-01NIH HHS R01-DK076683NIH HHS R01-DK105124, R01-DK136765, R01-LM013061, 2U01-HG008680, U01-AI152960, and 5UL1-TR001873NIH/NICHD 1R21-HD104176-01NIMHD NIH HHS L60 MD008562NLM NIH HHS R01 LM013061U.S. Department of Defense W81XWH-16-1-0451, W81XWH-22-1-0966US Department of Defense W81XWH-16-1-0451, W81XWH-22-1-0966
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39352759
PMCPMC11801752

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.