Evidence map›Paper›PMID 39354239›Full record

ArticleGeroScience2025

Association of a DASH diet and magnetoencephalography in dementia-free adults with different risk levels of Alzheimer's disease.

Alfredo Trabado-Fernández, Alejandra García-Colomo, Esther Cuadrado-Soto, África Peral-Suárez, María Dolores Salas-González, Ana María Lorenzo-Mora, Aránzazu Aparicio, María Luisa Delgado-Losada, Fernando Maestú-Unturbe, Ana M López-Sobaler

Abstract read
In one paragraph

Article in GeroScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alfredo Trabado-Fernández *Department of Nutrition and Food Science, Faculty of Pharmacy, Complutense University of Madrid, Pl. de Ramón y Cajal S/N, 28040, Madrid, Spain.ORCID 0000-0001-9300-3304
Alejandra García-Colomo *Department of Experimental Psychology, Cognitive Processes and Speech Therapy, Faculty of Psychology, Complutense University of Madrid, 28223, Madrid, Spain.ORCID 0000-0003-1817-6007
Esther Cuadrado-SotoDepartment of Nutrition and Food Science, Faculty of Pharmacy, Complutense University of Madrid, Pl. de Ramón y Cajal S/N, 28040, Madrid, Spain. esther.cuadrado@ucm.es.ORCID 0000-0002-4169-9925
África Peral-SuárezDepartment of Nutrition and Food Science, Faculty of Pharmacy, Complutense University of Madrid, Pl. de Ramón y Cajal S/N, 28040, Madrid, Spain.ORCID 0000-0002-2023-0298
María Dolores Salas-GonzálezDepartment of Nutrition and Food Science, Faculty of Pharmacy, Complutense University of Madrid, Pl. de Ramón y Cajal S/N, 28040, Madrid, Spain.ORCID 0000-0002-6110-7456
Ana María Lorenzo-MoraDepartment of Nutrition and Food Science, Faculty of Pharmacy, Complutense University of Madrid, Pl. de Ramón y Cajal S/N, 28040, Madrid, Spain.ORCID 0000-0002-1368-1971
Aránzazu AparicioDepartment of Nutrition and Food Science, Faculty of Pharmacy, Complutense University of Madrid, Pl. de Ramón y Cajal S/N, 28040, Madrid, Spain.ORCID 0000-0001-8500-9802
María Luisa Delgado-LosadaDepartment of Experimental Psychology, Cognitive Processes and Speech Therapy, Faculty of Psychology, Complutense University of Madrid, 28223, Madrid, Spain.ORCID 0000-0001-8808-4613
Fernando Maestú-UnturbeDepartment of Experimental Psychology, Cognitive Processes and Speech Therapy, Faculty of Psychology, Complutense University of Madrid, 28223, Madrid, Spain.ORCID 0000-0002-3195-0071
Ana M López-SobalerDepartment of Nutrition and Food Science, Faculty of Pharmacy, Complutense University of Madrid, Pl. de Ramón y Cajal S/N, 28040, Madrid, Spain.ORCID 0000-0002-4133-1450

Funding

Comunidad de Madrid CT19/23-INVM-74Ministerio de Economía y Competitividad PSI2015-68793-C3-1-RMinisterio de Universidades CT18/22Ministerio de Universidades PRE2019-087612
6 · The paper itself

Abstract

This study explored how adherence to the DASH diet relates to electrophysiological measures in individuals at varying Alzheimer's disease (AD) risk due to family history (FH). There were 179 dementia-free subjects. DASH index was calculated, and participants were classified into different DASH adherence groups. Tertiles of relative alpha power in default mode network (DMN) regions were calculated. Multivariate logistic regression models were used to examine the association. Lower DASH adherence was associated with decreased odds of higher relative alpha power in the DMN, observed across the entire sample and specifically among those without a FH of AD. Logistic regression models indicated that participants with poorer DASH adherence had a reduced likelihood of elevated DMN alpha power, potentially influenced by vascular and amyloid-beta mechanisms. These findings underscore the dietary pattern's potential role in neural activity modulation, particularly in individuals not genetically predisposed to AD.

Indexed as

Alzheimer DiseaseDietary Approaches To Stop HypertensionMagnetoencephalographyAgedFemaleHumansMaleMiddle AgedRisk FactorsAlzheimer’s diseaseCognitively unimpairedDASH dietDementiaMagnetoencephalography

Identifiers

PMID39354239
PMCPMC11979050

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.