Evidence mapPaperPMID 39355418Full record

ArticleIntegrative medicine (Encinitas, Calif.)2024

The Impact of Latihan Pasrah Diri / Self Surrender Practice (LPD) in Sleep Quality and Inflammatory Markers in Diabetes Mellitus Type 2 Patients Without Depression: A Randomized Controlled Trial.

Agus Siswanto, Ahmad Husain Asdie, Rico Novyanto, Laode Kardin, Yohana Sahara, David Yosua Kaban, Harik Firman Thahadian, Rakhmat Tajudin, Heriyanto Hidayat, Michael Dwinata

Abstract read
In one paragraph

Article in Integrative medicine (Encinitas, Calif.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Agus SiswantoPsychosomatic Division, Department of Internal Medicine, Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia.
Ahmad Husain AsdieEndocrine & Metabolic Division, Department of Internal Medicine, Faculty of Medicine, Gadjah Mada University, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia.
Rico NovyantoDepartment of Internal Medicine, Faculty of Medicine, Gadjah Mada University, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia.
Laode KardinDepartment of Internal Medicine, Faculty of Medicine, Gadjah Mada University, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia.
Yohana SaharaDepartment of Internal Medicine, Faculty of Medicine, Gadjah Mada University, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia.
David Yosua KabanDepartment of Internal Medicine, Faculty of Medicine, Gadjah Mada University, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia.
Harik Firman ThahadianDepartment of Internal Medicine, Faculty of Medicine, Gadjah Mada University, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia.
Rakhmat TajudinDepartment of Internal Medicine, Faculty of Medicine, Gadjah Mada University, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia.
Heriyanto HidayatDepartment of Internal Medicine, Faculty of Medicine, Gadjah Mada University, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia.
Michael DwinataDepartment of Internal Medicine, Faculty of Medicine, Gadjah Mada University, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Insomnia is more frequent in type 2 diabetes mellitus (T2DM) patients. Both conditions are known to cause low-grade inflammation and an independent risk factor for cardio-cerebrovascular events (CCDs) and overall mortality. Relaxation, mindfulness, breath control, and spiritual-based therapies such as Latihan Pasrah Diri / Self Surrender Practice (LPD) have been known to induce relaxation, improve depressive symptoms and sleep quality, inflammatory markers, glycemic control, Daily Living Activities (DLA), and Quality of Life (QoL) in T2DM patients. It is currently unknown whether LPD can improve sleep quality in patients with T2DM without depression and its association with inflammation. Objectives: Determine the effect of LPD on sleep quality and inflammatory markers in T2DM patients without depression. Method: This is a prospective, single-blind, randomized controlled trial. Patients aged 30-60 years old, Muslim, diagnosed with type 2 diabetes mellitus and who were not currently experiencing depression (Beck Depression Inventory-II Score <17) were eligible to be included in the study. We assessed the changes in the value of the ΔInsomnia Severity Score (ΔISI) and inflammatory markers (Δhs-CRP, ΔMPV, and ΔNLR). The intervention group was the group with standard therapy of DM and LPD, while the control group was the group with standard therapy of DM without LPD. The intervention was carried out 2 times a day with 20 minutes for each session, for 8 weeks. Result: A total of 44 subjects were randomized 1: 1 into intervention (n = 22) and control (n = 22) groups. In the intervention group, only 12 subjects met the minimum frequency of intervention, thus being included in the statistical analysis. There was a statistically significant decrease of ΔISI score by 2.58 compared to 0.04 ( Conclusion: Eight weeks of LPD improves sleep quality and reduces inflammatory markers (MPV and NLR) in T2DM patients without depression. Whether changes in inflammatory markers and insomnia are related and whether improvements in insomnia lead to improvements in inflammatory markers or vice versa requires further study. Limitations: Direct supervision on the diet and physical activity of the subjects was not done due to some obstacles in the field.

Identifiers

PMID39355418
PMCPMC11441587

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.