Evidence map›Paper›PMID 39355510›Full record

ArticleApplied physics reviews2024

Synthesis and characterization of amine-functionalized graphene as a nitric oxide-generating coating for vascular stents.

Tanveer A Tabish, Mian Zahid Hussain, Yangzhi Zhu, Jiabao Xu, Wei E Huang, Marina Diotallevi, Roger J Narayan, Mark J Crabtree, Ali Khademhosseini, Paul G Winyard and 1 more

Abstract read
In one paragraph

Article in Applied physics reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tanveer A TabishDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation (BHF) Centre of Research Excellence, University of Oxford, Headington, Oxford OX3 7BN, United Kingdom.ORCID https://orcid.org/0000-0001-5578-076X
Mian Zahid HussainSchool of Natural Sciences, Department of Chemistry, Chair of Inorganic and Metal-Organic Chemistry, Technical University of Munich (TUM), Lichtenbergstraße 4, 85748 Garching, Germany.ORCID https://orcid.org/0000-0003-3307-5925
Yangzhi ZhuTerasaki Institute for Biomedical Innovation, Los Angeles, California 90064, USA.ORCID https://orcid.org/0000-0003-2920-3365
Jiabao XuDepartment of Engineering Science, University of Oxford, Oxford OX1 3PJ, United Kingdom.ORCID https://orcid.org/0000-0002-1285-9408
Wei E HuangDepartment of Engineering Science, University of Oxford, Oxford OX1 3PJ, United Kingdom.ORCID https://orcid.org/0000-0003-1302-6528
Marina DiotalleviDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation (BHF) Centre of Research Excellence, University of Oxford, Headington, Oxford OX3 7BN, United Kingdom.ORCID https://orcid.org/0000-0001-7982-5678
Roger J NarayanJoint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Raleigh, North Carolina 27599, USA.ORCID https://orcid.org/0000-0002-2673-0939
Mark J CrabtreeDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation (BHF) Centre of Research Excellence, University of Oxford, Headington, Oxford OX3 7BN, United Kingdom.ORCID https://orcid.org/0000-0003-3298-2697
Ali KhademhosseiniTerasaki Institute for Biomedical Innovation, Los Angeles, California 90064, USA.ORCID https://orcid.org/0000-0002-2692-1524
Paul G WinyardUniversity of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter EX1 2LU, United Kingdom.ORCID https://orcid.org/0000-0002-9613-1202
Craig A LygateDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation (BHF) Centre of Research Excellence, University of Oxford, Headington, Oxford OX3 7BN, United Kingdom.ORCID https://orcid.org/0000-0001-6079-0284

Funding

British Heart Foundation FS/ATA/21/20015
6 · The paper itself

Abstract

Drug-eluting stents are commonly utilized for the treatment of coronary artery disease, where they maintain vessel patency and prevent restenosis. However, problems with prolonged vascular healing, late thrombosis, and neoatherosclerosis persist; these could potentially be addressed via the local generation of nitric oxide (NO) from endogenous substrates. Herein, we develop amine-functionalized graphene as a NO-generating coating on polylactic acid (PLA)-based bioresorbable stent materials. A novel catalyst was synthesized consisting of polyethyleneimine and polyethylene glycol bonded to graphene oxide (PEI-PEG@GO), with physicochemical characterization using x-ray diffraction, Raman spectroscopy, Fourier transform infrared spectroscopy, and thermogravimetric analysis. In the presence of 10

Identifiers

PMID39355510
PMCPMC7616654

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.