Evidence map›Paper›PMID 39355701›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2024

Development of non-pulmonary soft-tissue metastasis is not a poor prognostic indicator in dogs with metastatic appendicular osteosarcoma.

Gabrielle S Fontes, Kira L Bourne, Shay Bracha, Kaitlin M Curran, Matthew Cook, Janis M Lapsley, Hunter J Piegols, Laura E Selmic

Abstract read
PubMed Full text at PMC
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gabrielle S FontesDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Sreet, Columbus, Ohio 43221, USA (Fontes, Bracha, Cook, Lapsley, Piegols, Selmic); Department of Small Animal Clinical Science, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, Texas 77843, USA (Bourne); Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, 700 SW 30th Street, Corvallis, Oregon 97331, USA (Curran).
Kira L BourneDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Sreet, Columbus, Ohio 43221, USA (Fontes, Bracha, Cook, Lapsley, Piegols, Selmic); Department of Small Animal Clinical Science, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, Texas 77843, USA (Bourne); Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, 700 SW 30th Street, Corvallis, Oregon 97331, USA (Curran).
Shay BrachaDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Sreet, Columbus, Ohio 43221, USA (Fontes, Bracha, Cook, Lapsley, Piegols, Selmic); Department of Small Animal Clinical Science, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, Texas 77843, USA (Bourne); Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, 700 SW 30th Street, Corvallis, Oregon 97331, USA (Curran).
Kaitlin M CurranDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Sreet, Columbus, Ohio 43221, USA (Fontes, Bracha, Cook, Lapsley, Piegols, Selmic); Department of Small Animal Clinical Science, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, Texas 77843, USA (Bourne); Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, 700 SW 30th Street, Corvallis, Oregon 97331, USA (Curran).
Matthew CookDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Sreet, Columbus, Ohio 43221, USA (Fontes, Bracha, Cook, Lapsley, Piegols, Selmic); Department of Small Animal Clinical Science, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, Texas 77843, USA (Bourne); Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, 700 SW 30th Street, Corvallis, Oregon 97331, USA (Curran).
Janis M LapsleyDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Sreet, Columbus, Ohio 43221, USA (Fontes, Bracha, Cook, Lapsley, Piegols, Selmic); Department of Small Animal Clinical Science, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, Texas 77843, USA (Bourne); Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, 700 SW 30th Street, Corvallis, Oregon 97331, USA (Curran).
Hunter J PiegolsDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Sreet, Columbus, Ohio 43221, USA (Fontes, Bracha, Cook, Lapsley, Piegols, Selmic); Department of Small Animal Clinical Science, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, Texas 77843, USA (Bourne); Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, 700 SW 30th Street, Corvallis, Oregon 97331, USA (Curran).
Laura E SelmicDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp Sreet, Columbus, Ohio 43221, USA (Fontes, Bracha, Cook, Lapsley, Piegols, Selmic); Department of Small Animal Clinical Science, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, Texas 77843, USA (Bourne); Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, 700 SW 30th Street, Corvallis, Oregon 97331, USA (Curran).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate whether patient factors affect development of non-pulmonary soft-tissue metastases following treatment of canine appendicular osteosarcoma and to report and compare outcomes to those in dogs with pulmonary or osseous metastases. Animals and procedure: The records of 3 veterinary teaching hospitals were reviewed to identify dogs that received definitive treatment for a primary appendicular osteosarcoma lesion and chemotherapy between January 2010 and June 2022. Dogs with non-pulmonary metastases following initial treatment were included. Descriptive statistics were calculated to summarize signalment information, and metastasis and survival times were compared between groups using Kaplan-Meier survival analysis and log-rank tests. Results: Thirty-six and 109 dogs developed non-pulmonary soft-tissue metastases and pulmonary or osseous metastases, respectively, following initial treatment. No patient factors were significantly associated with development of non-pulmonary soft-tissue metastases. The median times to non-pulmonary soft-tissue metastasis or initial pulmonary or osseous metastasis were 220 and 169 d, respectively ( Conclusion: Dogs with non-pulmonary soft-tissue metastases had similar disease-free intervals and survival rates to dogs with typical pulmonary or osseous metastases.

Indexed as

Bone NeoplasmsDog DiseasesOsteosarcomaSoft Tissue NeoplasmsAnimalsDogsFemaleLung NeoplasmsMalePrognosisRetrospective Studies

Identifiers

PMID39355701
PMCPMC11411482

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.